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儿童孤立性眶部肌纤维瘤:附 1 例报告并文献复习

Solitary orbital myofibroma in a child: A rare case report with literature review.

机构信息

Ophthalmic Plastic Surgery, Orbit and Ocular Oncology Services, The Operation Eyesight Universal Institute for Eye Cancer, Bhubaneswar, Odisha, India.

Kanupriya Dalmia Ophthalmic Pathology Laboratory, L.V. Prasad Eye Institute, Mithu Tulsi Chanrai Campus, Bhubaneswar, Odisha, India.

出版信息

Indian J Ophthalmol. 2019 Jul;67(7):1240-1245. doi: 10.4103/ijo.IJO_1553_18.

Abstract

Myofibroma is a rare benign mesenchymal tumor of uncertain histogenesis. A six-year-old boy presented with a unilateral lower eyelid mass of six weeks' duration. MRI revealed a circumscribed mass in the inferolateral orbit with bony erosion. A systemic examination was unremarkable. Excision with histopathology revealed a partially infiltrative spindle cell tumor with bland nuclear morphology expressing smooth muscle actin and muscle-specific actin, compatible with myofibroma. Solitary myofibroma is a rare childhood orbital tumor and may clinico-radiologically closely mimic a malignancy. Histopathology and immunohistochemistry can help reach a definitive diagnosis. Systemic evaluation and close follow up are crucial in such cases.

摘要

肌纤维瘤是一种罕见的良性间叶组织肿瘤,其组织发生尚不确定。一名 6 岁男孩因单侧下眼睑肿块 6 周就诊。MRI 显示在下外侧眼眶有一个边界清楚的肿块,并伴有骨侵蚀。全身检查无异常。组织病理学检查显示部分浸润性梭形细胞肿瘤,细胞核形态温和,表达平滑肌肌动蛋白和肌肉特异性肌动蛋白,符合肌纤维瘤。孤立性肌纤维瘤是一种罕见的儿童眼眶肿瘤,在临床和影像学上可能与恶性肿瘤非常相似。组织病理学和免疫组织化学检查有助于明确诊断。在这种情况下,系统评估和密切随访至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5735/6611317/7352bf7c74d4/IJO-67-1240-g001.jpg

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