利用 AIMs-InDels 对厄瓜多尔人群进行三联体遗传组成分析，与常染色体、线粒体 DNA 和 Y 染色体数据进行比较。
The three-hybrid genetic composition of an Ecuadorian population using AIMs-InDels compared with autosomes, mitochondrial DNA and Y chromosome data.
机构信息
Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Av. Mariscal Sucre and Mariana de Jesús, Block I, Quito, 170129, Ecuador.
Laboratorio de Genética, Centros Médicos Especializados Cruz Roja Ecuatoriana, Papallacta oe1-66, Quito, 170512, Ecuador.
出版信息
Sci Rep. 2019 Jun 25;9(1):9247. doi: 10.1038/s41598-019-45723-w.
The history of Ecuador was marked by the arrival of Europeans with Africans, resulting in the mixture of Native Americans with Africans and Europeans. The present study contributes to the knowledge of the Ecuadorian mestizo population by offering information about ancestry and ethnic heterogeneity. Forty-six AIM-InDels (Ancestry Informative Insertion/Deletion Markers) were used to obtain information on 240 Ecuadorian individuals from three regions (Amazonia, the Highlands, and the Coast). As a result, the population involved a significant contribution from Native Americans (values up to 51%), followed by Europeans (values up to 33%) and Africans (values up to 13%). Furthermore, we compared the data obtained with nine previously reported scientific articles on autosomal, mitochondrial DNA and Y chromosomes. The admixture results correspond to Ecuador's historical background and vary slightly between regions.
厄瓜多尔的历史以欧洲人与非洲人的到来为标志，导致了美洲原住民与非洲人和欧洲人的混合。本研究通过提供关于祖先和族裔异质性的信息，为了解厄瓜多尔混血人群做出了贡献。使用了 46 个 AIM-InDels（祖先信息插入/缺失标记）来获取来自三个地区（亚马逊地区、高地和海岸）的 240 名厄瓜多尔个体的信息。结果表明，该人群中美洲原住民的贡献非常显著（高达 51%），其次是欧洲人（高达 33%）和非洲人（高达 13%）。此外，我们将获得的数据与九篇以前关于常染色体、线粒体 DNA 和 Y 染色体的科学文章进行了比较。混合的结果与厄瓜多尔的历史背景相符，并且在不同地区略有差异。
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