Steece K A, DeLeon-Jones F A, Lee J M, Ritzmann R F
Neurobiology Laboratories, West Side VA Hospital, University of Illinois, Chicago.
NIDA Res Monogr. 1986;75:583-6.
Morphine and enkephalins act preferentially via different receptors, mu and delta, respectively. Chronic administration of morphine or methionine enkephalin results in development of physical dependence. Data from our laboratory suggests that there are some differences in the effect of these two opioids with regards to certain neurochemical systems.
吗啡和脑啡肽分别主要通过不同的受体,即μ受体和δ受体起作用。长期给予吗啡或甲硫氨酸脑啡肽会导致身体依赖性的形成。我们实验室的数据表明,这两种阿片类药物在某些神经化学系统方面的作用存在一些差异。