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疑似嗜酸性粒细胞性脑脊髓炎继发于嗜酸性粒细胞性脑膜炎,临床预后良好。

Severe Eosinophilic Meningoencephalitis Secondary to Suspected Neuroangiostrongyliasis with a Good Clinical Outcome.

作者信息

Chiong Fabian, Lloyd Andrew R, Post Jeffrey J

机构信息

Department of Infectious Diseases, Prince of Wales Hospital, Sydney, NSW, Australia.

Prince of Wales Clinical School, University of New South Wales, Sydney, NSW, Australia.

出版信息

Case Rep Infect Dis. 2019 May 26;2019:4037196. doi: 10.1155/2019/4037196. eCollection 2019.

DOI:10.1155/2019/4037196
PMID:31240141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6556351/
Abstract

has caused sporadic cases of eosinophilic meningoencephalitis in Sydney, Australia. We describe a 36-year-old man who presented subacutely with fevers, reduced level of consciousness, confusion, ophthalmoplegia, and urinary incontinence. He was diagnosed with severe eosinophilic meningoencephalitis secondary to suspected based on clinical, serological, and radiological findings. The patient was treated with albendazole and prednisolone with full neurological recovery. Management of neuroangiostrongyliasis with anthelminthic is controversial as it is thought to cause worsened outcomes through inciting an inflammatory response as a result of parasite killing. We managed to successfully treat our patient using albendazole and prednisolone and achieved a good outcome.

摘要

在澳大利亚悉尼引发了散发性嗜酸性粒细胞性脑膜脑炎病例。我们描述了一名36岁男性,他亚急性起病,伴有发热、意识水平下降、意识模糊、眼肌麻痹和尿失禁。根据临床、血清学和影像学检查结果,他被诊断为疑似继发的严重嗜酸性粒细胞性脑膜脑炎。该患者接受了阿苯达唑和泼尼松龙治疗,神经功能完全恢复。用驱虫药治疗嗜酸性粒细胞性脑膜脑炎存在争议,因为人们认为它会因杀死寄生虫引发炎症反应而导致病情恶化。我们成功地用阿苯达唑和泼尼松龙治疗了我们的患者,并取得了良好的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcfc/6556351/1d1c32e4c805/CRIID2019-4037196.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcfc/6556351/262d20618c47/CRIID2019-4037196.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcfc/6556351/1d1c32e4c805/CRIID2019-4037196.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcfc/6556351/262d20618c47/CRIID2019-4037196.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcfc/6556351/1d1c32e4c805/CRIID2019-4037196.002.jpg

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Parasitology. 2016 Aug;143(9):1087-118. doi: 10.1017/S0031182016000652. Epub 2016 May 26.
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Severe hemorrhagic meningoencephalitis due to Angiostrongylus cantonensis among young children in Sydney, Australia.
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Am J Trop Med Hyg. 2009 Sep;81(3):443-5.
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