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利伐沙班在治疗外周动脉疾病患者中是否有作用?

Does rivaroxaban have a role in treating patients with PAD?

作者信息

Thomas Rebekah

机构信息

Rebekah Thomas is assistant program director, Georgia campus site director, and an assistant professor in the PA program at Philadelphia College of Osteopathic Medicine in Suwanee, Ga. The author has disclosed no potential conflicts of interest, financial or otherwise.

出版信息

JAAPA. 2019 Jul;32(7):16-17. doi: 10.1097/01.JAA.0000558364.85986.ad.

DOI:10.1097/01.JAA.0000558364.85986.ad
PMID:31241606
Abstract

Peripheral arterial disease can cause devastating health outcomes, and few therapies are available to treat this condition. Results of a secondary analysis of the COMPASS trial suggest benefit with the use of rivaroxaban 2.5 mg twice daily plus aspirin 100 mg daily. This treatment regimen could change the standard pharmacotherapeutic management practice for many patients with peripheral arterial disease.

摘要

外周动脉疾病可导致严重的健康后果,而治疗这种疾病的疗法很少。COMPASS试验的二次分析结果表明,每日两次服用2.5毫克利伐沙班加每日服用100毫克阿司匹林有益。这种治疗方案可能会改变许多外周动脉疾病患者的标准药物治疗管理实践。

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引用本文的文献

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Reducing residual thrombotic risk in patients with peripheral artery disease: impact of the COMPASS trial.降低外周动脉疾病患者的残余血栓形成风险:COMPASS试验的影响
Drugs Context. 2020 Jul 6;9. doi: 10.7573/dic.2020-5-5. eCollection 2020.