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全国基底细胞癌光动力疗法项目总体结果:将新技术引入社会医疗保健的多中心临床研究。

Overall Results for a National Program of Photodynamic Therapy for Basal Cell Carcinoma: A Multicenter Clinical Study to Bring New Techniques to Social Health Care.

机构信息

1 São Carlos Institute of Physics, University of São Paulo (USP), São Carlos, São Paulo, Brazil.

2 Instituto Federal de Alagoas, Campus Piranhas, Brazil.

出版信息

Cancer Control. 2019 Jan-Dec;26(1):1073274819856885. doi: 10.1177/1073274819856885.

DOI:10.1177/1073274819856885
PMID:31242758
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6598334/
Abstract

Along the past years, a national program to implement photodynamic therapy (PDT) for nonmelanoma skin cancer (NMSC) was performed over the Brazilian territory. Using a strategy involving companies, national bank, and medical partners, equipment, medication, and protocols were tested in a multicenter study. With results collected over 6 years, we could reach a great deal of advances concerning the use of PDT for skin cancer. We present the overall reached results of the program and discuss several aspects about it, including public politics of treatment. A discussion about advantages of this technique within conditions of health care is placed, comparing PDT with surgery, including an analysis about the implementation of PDT in countries in development as Brazil, considering not only technical but social aspects, as the distribution of medical doctor in the Brazilian territory. The program resulted in a huge dissemination of PDT in Brazil and many countries in Latin America, in a partnership among public politics, universities, companies, and hospitals and clinics and in the insertion of national technologies as option to treat NMSC. Consequence of the program is mainly the continuation of the use of PDT in Brazil and many countries in Latin America.

摘要

在过去的几年里,巴西在全国范围内实施了一项针对非黑色素瘤皮肤癌(NMSC)的光动力疗法(PDT)计划。通过采用涉及公司、国家银行和医疗合作伙伴的策略,在一项多中心研究中对设备、药物和方案进行了测试。通过收集 6 年的数据,我们在 PDT 治疗皮肤癌方面取得了重大进展。我们展示了该计划的总体成果,并讨论了计划的几个方面,包括治疗的公共政策。我们将讨论在医疗保健条件下,与手术相比 PDT 的优势,包括对发展中国家(如巴西)实施 PDT 的分析,不仅考虑了技术方面,还考虑了社会方面,如巴西领土上的医生分布。该计划在巴西和许多拉丁美洲国家广泛推广了 PDT,并在公共政策、大学、公司、医院和诊所之间建立了合作伙伴关系,将国家技术作为治疗 NMSC 的选择。该计划的结果主要是 PDT 在巴西和许多拉丁美洲国家的继续使用。

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