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比较老年人残疾发展的身体和社会风险降低因素:一项基于人群的队列研究。

Comparison of physical and social risk-reducing factors for the development of disability in older adults: a population-based cohort study.

机构信息

Department of Behavioural Science and Health, University College London Research Department of Epidemiology and Public Health, London, UK

Department of Behavioural Science and Health, University College London Research Department of Epidemiology and Public Health, London, UK.

出版信息

J Epidemiol Community Health. 2019 Oct;73(10):906-912. doi: 10.1136/jech-2019-212372. Epub 2019 Jun 26.

Abstract

BACKGROUND

Considerations of modifiable risk factors for the development of disability in older age have traditionally focused on physical activity. However, there is increasing evidence that psychological, social, and cognitive factors also help to maintain functional independence. This study compared the protective associations between physical and social activities and disability onset.

METHODS

We analysed data from 5434 adults aged 50+ years tracked biennially from 2004/2005 to 2016/2017, measuring self-reported difficulty in carrying out any basic activities of daily living (ADLs) or instrumental ADLs. Exposures included mild, moderate and vigorous physical activity, frequency of socialising with friends/family, cultural engagement (eg, going to the theatre/museums/concerts), and participation in community groups.

RESULTS

Over the 12-year follow-up, 1945 adults developed disability. Using Cox proportional hazards regression models adjusted for all identified demographic and health-related variables, vigorous exercise or activity once a month or more (HR 0.82, 95% CI 0.71 to 0.96), moderate exercise or activity more than once a week (HR 0.81, 95% CI 0.67 to 0.97) or cultural engagement once or twice a year or more (HR 0.84, 95% CI 0.73 to 0.97) were associated with a lower hazard of developing disability. Other exposures did not show independent protective associations. Results were robust to sensitivity analyses considering reverse causality and exploring the potential confounding role of time-invariant factors, such as socioeconomic status.

CONCLUSION

These results suggest the importance of either developing multimodal interventions to protect against disability and promote healthy ageing or promoting greater physical and social engagement with existing community activities among older adults.

摘要

背景

在考虑导致老年人残疾的可改变风险因素时,传统上主要关注身体活动。然而,越来越多的证据表明,心理、社会和认知因素也有助于保持功能独立性。本研究比较了身体活动和社会活动与残疾发生之间的保护关联。

方法

我们分析了 5434 名年龄在 50 岁及以上的成年人的数据,这些成年人从 2004/2005 年至 2016/2017 年每两年跟踪一次,测量自我报告的进行任何基本日常生活活动(ADL)或工具性 ADL 的困难程度。暴露因素包括轻度、中度和剧烈的身体活动、与朋友/家人社交的频率、文化参与(例如,去剧院/博物馆/音乐会)以及参与社区团体。

结果

在 12 年的随访期间,有 1945 名成年人出现残疾。使用调整了所有确定的人口统计学和健康相关变量的 Cox 比例风险回归模型,每月或更多次剧烈运动或活动(HR 0.82,95%CI 0.71 至 0.96)、每周多次中度运动或活动(HR 0.81,95%CI 0.67 至 0.97)或每年一到两次或更多次文化参与(HR 0.84,95%CI 0.73 至 0.97)与残疾发生的风险较低相关。其他暴露因素没有显示出独立的保护关联。考虑到反向因果关系和探索社会经济地位等时不变因素的潜在混杂作用的敏感性分析结果稳健。

结论

这些结果表明,对于老年人,要么开发多模式干预措施以预防残疾和促进健康老龄化,要么促进更多的身体和社会参与现有的社区活动,这一点非常重要。

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