Boruah Pranjal, Saqib Najam, Barooah Jumee, Baruah Dhiraj, Sharma Parikshit
Cardiology, Geisinger Commonwealth School of Medicine, Wright Center for Graduate Medical Education, Scranton, USA.
Internal Medicine, Wright Center for Graduate Medical Education, Scranton, USA.
Cureus. 2019 Apr 5;11(4):e4399. doi: 10.7759/cureus.4399.
Left ventricular assist devices (LVADs) have revolutionized therapy for patients with Stage D heart failure (HF) with reduced systolic function providing not only improved survival benefits but also meaningful changes in quality of life and functional capacity. With technological advances and improved durability of devices, length of survival has significantly improved. With continued organ donor shortage, LVADs are frequently serving as a substitute for cardiac transplant as destination therapy, particularly among the elderly. Internists not only face the important challenge of identifying the patients in need referral for these advanced therapies, they are also faced with the challenges of taking care of these patients. This review will help the internists to better understand the present status, indications and advances in LVADs and also understand the complications and adverse effects associated with these devices.
左心室辅助装置(LVADs)彻底改变了对收缩功能降低的D期心力衰竭(HF)患者的治疗方法,不仅提高了生存率,还显著改善了生活质量和功能能力。随着技术进步和装置耐用性的提高,生存时间已显著延长。由于器官供体持续短缺,LVADs经常作为心脏移植的替代方案用于终末期治疗,尤其是在老年患者中。内科医生不仅面临着识别需要转诊接受这些先进治疗的患者这一重要挑战,还面临着照顾这些患者的挑战。本综述将帮助内科医生更好地了解LVADs的现状、适应症和进展,同时了解与这些装置相关的并发症和不良反应。