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黑腹果蝇中的基因剂量补偿

Gene dosage compensation in Drosophila melanogaster.

作者信息

Lucchesi J C, Manning J E

机构信息

Department of Biology, University of North Carolina, Chapel Hill 27514.

出版信息

Adv Genet. 1987;24:371-429. doi: 10.1016/s0065-2660(08)60013-9.

DOI:10.1016/s0065-2660(08)60013-9
PMID:3124533
Abstract

The comparative lack of sexual dimorphism of apricot and other [sex-linked] genes studied is due to "sex-limitation", i.e., to a compensatory influence of the dosage difference between the sexes in respect to other genes in the X-chromosome. The facts are of particular interest from an evolutionary standpoint.

摘要

所研究的杏色基因和其他[性连锁]基因相对缺乏性二态性,这是由于“性限制”,即X染色体上其他基因在性别间剂量差异的补偿性影响。从进化的角度来看,这些事实特别有趣。

相似文献

1
Gene dosage compensation in Drosophila melanogaster.黑腹果蝇中的基因剂量补偿
Adv Genet. 1987;24:371-429. doi: 10.1016/s0065-2660(08)60013-9.
2
The link between dosage compensation and sex differentiation in Drosophila melanogaster.黑腹果蝇中剂量补偿与性别分化之间的联系。
Chromosoma. 1981;82(2):217-27. doi: 10.1007/BF00286106.
3
Sex Chromosome-wide Transcriptional Suppression and Compensatory Cis-Regulatory Evolution Mediate Gene Expression in the Drosophila Male Germline.性染色体全范围转录抑制和补偿性顺式调控进化介导果蝇雄性生殖系中的基因表达。
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4
Dosage compensation of x-chromosome activity in interspecific hybrids of Drosophila melanogaster and D. simulans.黑腹果蝇和拟暗果蝇种间杂种中X染色体活性的剂量补偿
Chromosoma. 1981;82(2):229-36. doi: 10.1007/BF00286107.
5
Genetic analysis of modifiers affecting sexual dimorphism and temperature sensitivity of bx1 in Drosophila melanogaster.影响黑腹果蝇bx1的性二态性和温度敏感性的修饰因子的遗传分析。
Dev Genet. 1989;10(2):106-11. doi: 10.1002/dvg.1020100206.
6
Sex determination compared in Drosophila and Caenorhabditis.果蝇和秀丽隐杆线虫性别决定的比较
Nature. 1990 Apr 19;344(6268):721-8. doi: 10.1038/344721a0.
7
Variation in the X:Autosome Distribution of Male-Biased Genes among Drosophila melanogaster Tissues and Its Relationship with Dosage Compensation.黑腹果蝇组织中雄性偏好基因的X染色体与常染色体分布差异及其与剂量补偿的关系
Genome Biol Evol. 2015 Jun 24;7(7):1960-71. doi: 10.1093/gbe/evv117.
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Sex-specific trans-regulatory variation on the Drosophila melanogaster X chromosome.黑腹果蝇X染色体上的性别特异性反式调控变异
PLoS Genet. 2015 Feb 13;11(2):e1005015. doi: 10.1371/journal.pgen.1005015. eCollection 2015 Feb.
9
The interaction between daughterless and sex-lethal in triploids: a lethal sex-transforming maternal effect linking sex determination and dosage compensation in Drosophila melanogaster.三倍体中无女儿基因与性致死基因之间的相互作用:一种致命的性别转化母体效应,将黑腹果蝇的性别决定与剂量补偿联系起来。
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10
Upstream sequences of dosage-compensated and non-compensated alleles of the larval secretion protein gene Sgs-4 in Drosophila.果蝇幼虫分泌蛋白基因Sgs-4的剂量补偿和非补偿等位基因的上游序列。
Chromosoma. 1987;96(1):1-7. doi: 10.1007/BF00285876.

引用本文的文献

1
The gene fl(2)d is required for various Sxl-controlled processes in Drosophila females.基因fl(2)d是果蝇雌性中各种由性梳减少基因(Sxl)控制的过程所必需的。
Rouxs Arch Dev Biol. 1991 Aug;200(3):172-176. doi: 10.1007/BF00190237.
2
The temperature-sensitive mutation vir (virilizer) identifies a new gene involved in sex determination of Drosophila.温度敏感突变vir(雄性化因子)鉴定出一个参与果蝇性别决定的新基因。
Rouxs Arch Dev Biol. 1991 Nov;200(5):240-248. doi: 10.1007/BF00241293.
3
Further analysis on the male-specific lethal mutations that affect dosage compensation in Drosophila melanogaster.
对影响黑腹果蝇剂量补偿的雄性特异性致死突变的进一步分析。
Rouxs Arch Dev Biol. 1989 May;198(1):34-38. doi: 10.1007/BF00376368.
4
Dosage Compensation in Drosophila-a Model for the Coordinate Regulation of Transcription.果蝇中的剂量补偿——转录协同调控的模型
Genetics. 2016 Oct;204(2):435-450. doi: 10.1534/genetics.115.185108.
5
Dosage compensation in Drosophila.果蝇中的剂量补偿效应。
Cold Spring Harb Perspect Biol. 2015 May 1;7(5):a019398. doi: 10.1101/cshperspect.a019398.
6
Effects of genome-wide copy number variation on expression in mammalian cells.全基因组拷贝数变异对哺乳动物细胞表达的影响。
BMC Genomics. 2011 Nov 16;12:562. doi: 10.1186/1471-2164-12-562.
7
Abnormal dosage compensation of reporter genes driven by the Drosophila glass multiple reporter (GMR) enhancer-promoter.异常剂量补偿的报告基因由果蝇玻璃多报告(GMR)增强子-启动子驱动。
PLoS One. 2011;6(5):e20455. doi: 10.1371/journal.pone.0020455. Epub 2011 May 31.
8
The non-dosage compensated Lsp1alpha gene of Drosophila melanogaster escapes acetylation by MOF in larval fat body nuclei, but is flanked by two dosage compensated genes.果蝇的非剂量补偿Lsp1alpha基因在幼虫脂肪体细胞核中逃避了MOF介导的乙酰化作用,但它两侧有两个剂量补偿基因。
BMC Mol Biol. 2007 May 19;8:35. doi: 10.1186/1471-2199-8-35.
9
The Drosophila GAGA factor is required for dosage compensation in males and for the formation of the male-specific-lethal complex chromatin entry site at 12DE.果蝇的GAGA因子对于雄性的剂量补偿以及在12DE处形成雄性特异性致死复合物染色质进入位点是必需的。
Genetics. 2004 Jan;166(1):279-89. doi: 10.1534/genetics.166.1.279.
10
Role of the male specific lethal (msl) genes in modifying the effects of sex chromosomal dosage in Drosophila.雄性特异性致死(msl)基因在调节果蝇性染色体剂量效应中的作用。
Genetics. 1999 May;152(1):249-68. doi: 10.1093/genetics/152.1.249.