Hermanussen Michael, Mumm Rebekka, Rintisch Aileen, Tutkuviene Janina, Suchomlinov Andrej, Joubert Kálmán, Longas Angel Ferrandez, Scheffler Christiane
Aschauhof 3, 24340 Altenhof-Eckernförde, Germany, E-mail:
University of Potsdam, Human Biology, 14469 Potsdam, Germany.
Pediatr Endocrinol Rev. 2019 Jun;16(4):457-467. doi: 10.17458/per.vol16.2019.hmr.heightsdschanges.
Growth is volatile and non-linear. Assessing the instantaneous speed of growth (momentary height velocity) depends on the precision and the number of measurements and the duration of the observation period. Measurements at short intervals reflect both the non-linearity of growth and the technical error of measurements (TEM).
We reanalyzed longitudinal measurements of body length at age 0, 3 months, 6 months, 9 months, 12 months, 18 months, and 24 months, from 1879 healthy infants (956 girls, 923 boys) from France (180 girls, 173 boys), Vilnius, Lithuania (507 girls, 507 boys), Lublin, Poland (67 girls, 56 boys), Zürich, Switzerland (94 girls, 102 boys) and Spain (108 girls, 95 boys); and longitudinal measurements of annual body height from age 2 to 18 years from 1528 healthy children and adolescents (774 girls, 754 boys) from France (41 girls, 47 boys), Vilnius, Lithuania (23 girls, 27 boys), Lublin, Poland (70 girls, 58 boys), Zürich, Switzerland (111 girls, 120 boys), Spain (94 girls, 74 boys), the Czech Republic (65 girls, 69 boys), Hungary (316 girls, 320 boys), and Berkeley, USA (54 girls, 39 boys).
We calculated age - and sex-specific mean values for height and SD for height separately for each country. In addition, we defined the instantaneous speed of growth by the difference of two measures of hSDS Formulas References A1 , or in the case of multiple measurements, by the slope of the linear regression (βhSDS(t)). Based on the longitudinal measurements of body length, we present reference values for annual growth velocity given in the form of SD of annual hSDS changes (ΔhSDS), from birth to maturity. Correction factors are added for validating measurements obtained at intervals of less than one year. The correction factors depend on number of measurements, and duration of the observation period.
生长是不稳定且非线性的。评估生长的瞬时速度（瞬时身高速度）取决于测量的精度、测量次数以及观察期的时长。短时间间隔的测量既反映了生长的非线性，也反映了测量技术误差（TEM）。
我们重新分析了来自法国（180名女孩，173名男孩）、立陶宛维尔纽斯（507名女孩，507名男孩）、波兰卢布林（67名女孩，56名男孩）、瑞士苏黎世（94名女孩，102名男孩）和西班牙（108名女孩，95名男孩）的1879名健康婴儿（956名女孩，923名男孩）在0、3、6、9、12、18和24个月龄时的身长纵向测量数据；以及来自法国（41名女孩，47名男孩）、立陶宛维尔纽斯（23名女孩，27名男孩）、波兰卢布林（70名女孩，58名男孩）、瑞士苏黎世（111名女孩，120名男孩）、西班牙（94名女孩，74名男孩）、捷克共和国（65名女孩，69名男孩）、匈牙利（316名女孩，320名男孩）和美国伯克利（54名女孩，39名男孩）的1528名健康儿童和青少年（774名女孩，754名男孩）在2至18岁时的年身高纵向测量数据。
我们分别计算了每个国家身高的年龄和性别特异性均值以及身高标准差。此外，我们通过hSDS公式参考文献A1中两种测量值的差值来定义生长的瞬时速度，或者在多次测量的情况下，通过线性回归的斜率（βhSDS(t)）来定义。基于身长的纵向测量数据，我们给出了从出生到成熟阶段以年hSDS变化标准差（ΔhSDS）形式呈现的年生长速度参考值。对于间隔小于一年获得的数据，添加了校正因子以验证测量结果。校正因子取决于测量次数和观察期的时长。
