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先天性白内障儿童中后葡萄肿的存在。

Presence of Posterior Staphyloma in Congenital Cataract Children.

机构信息

Department of Ophthalmology, Eye Institute of Eye and Ear, Nose, and Throat Hospital of Fudan University, Shanghai, China.

NHC Key Laboratory of Myopia, Fudan University, Shanghai, China.

出版信息

Curr Eye Res. 2019 Dec;44(12):1319-1324. doi: 10.1080/02713683.2019.1637437. Epub 2019 Jul 5.

Abstract

: To investigate the prevalence of posterior staphyloma (PS) in congenital cataract children and its role in predicting postoperative axial elongation.: Preoperative prevalence of PS in 520 congenital cataract patients was reviewed and compared with that of the healthy eyes of 300 unilateral traumatic cataract children after 1:1 propensity score matching. Then, 32 pseudophakic children with preoperative PS and 48 age-matched pseudophakic controls without preoperative PS were followed up after the surgery, to compare their axial growth rates and refractive changes.: Congenital cataract was significantly associated with the presence of PS (OR: 14.88, = .009) after propensity score matching. Even in congenital cataract eyes with axial length <26 mm, 5% were identified with PS on B-scan: ≤22 mm: 3%, 22-24 mm: 5% and 24-26 mm: 13%. Eyes with preoperative PS exhibited faster postoperative axial growth than those without, especially in bilateral cases or in children undergoing surgery before 8 years old (≤4 years: 0.53 ± 0.33 vs 0.30 ± 0.21 mm/y = .028; 4-8 years: 0.37 ± 0.26 vs 0.23 ± 0.15 mm/y = .044). Myopic shift after surgery was also more significant in children with preoperative PS than in those without (-1.10 ± 0.50 vs -0.60 ± 0.47D/y, < .001).: Congenital cataract is a risk factor for PS. Preoperative PS in pediatric cataract eyes may be an indicator of excessive postoperative axial elongation, especially in bilateral cases or in cases undergoing cataract surgery at a younger age. Our findings may also promote better clinical decision-making in intraocular lens power selection for pediatric population.

摘要

: 研究先天性白内障儿童后发性葡萄肿(PS)的患病率及其在预测术后轴性伸长中的作用。

: 回顾了 520 例先天性白内障患者的术前 PS 患病率,并与 300 例单侧外伤性白内障儿童的健康眼进行了 1:1 倾向评分匹配后的患病率进行了比较。然后,对 32 例术前有 PS 的假性白内障儿童和 48 例年龄匹配的术前无 PS 的假性白内障对照儿童进行了随访,比较了他们的轴向生长率和屈光变化。

: 倾向评分匹配后,先天性白内障与 PS 的存在显著相关(OR:14.88, =.009)。即使在眼轴长度<26mm 的先天性白内障眼中,仍有 5%的患者在 B 超上发现 PS:≤22mm:3%,22-24mm:5%,24-26mm:13%。术前有 PS 的眼术后轴向生长较快,尤其是双侧或 8 岁以下(≤4 岁:0.53±0.33 比 0.30±0.21mm/y, =.028;4-8 岁:0.37±0.26 比 0.23±0.15mm/y, =.044)。术前有 PS 的儿童术后近视漂移也比无 PS 的儿童更明显(-1.10±0.50 比-0.60±0.47D/y, <.001)。

: 先天性白内障是 PS 的危险因素。小儿白内障眼中的术前 PS 可能是术后轴性伸长过度的指标,尤其是双侧或年龄较小行白内障手术的病例。我们的研究结果也可能有助于小儿人群人工晶状体屈光力选择的临床决策。

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