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高分辨率硅阵列探测器在永磁体系统磁场中的性能可行性研究。

A feasibility study for high-resolution silicon array detector performance in the magnetic field of a permanent magnet system.

机构信息

Centre for Medical Radiation Physics, University of Wollongong, New South Wales (NSW), Wollongong, 2522, Australia.

Ingham Institute for Applied Medical Research, Liverpool, NSW, 2170, Australia.

出版信息

Med Phys. 2019 Sep;46(9):4224-4232. doi: 10.1002/mp.13686. Epub 2019 Jul 12.

Abstract

PURPOSE

Magnetic field effects on dose distribution and detector functionality must be well understood. The detector utilized to investigate these magnetic field effects was the DUO silicon array detector; the performance of this high spatial resolution detector was assessed under these conditions. The results were compared to Gafchromic EBT3 film to highlight any intrinsic magnetic field effects in the silicon. The results were also compared to previously published MagicPlate-512 (M512) data. The DUO has an improved spatial resolution (200 µm) over the M512 (2 mm).

METHODS

A permanent magnet named Magnetic Apparatus for RaDiation Oncology Studies (MARDOS) paired with a standard linear accelerator (linac) enables either transverse (1.2 T) or inline (0.95 T) orientations of the magnetic field with respect to the radiation beam. A 6 MV Varian 2100C Linac provided the radiation component for the measurements. The DUO detector has 505 sensitive volumes (each volume measuring 800 × 40 × 100 µm ) organized in two orthogonal, linear arrays. The DUO was embedded in a solid water phantom in the first set-up and then a solid lung phantom in the second set-up and placed between the magnet cones. Beam profiles were compared under the magnetic field conditions and 0 T. Small field sizes from 0.8 × 0.8 cm up to 2.3 × 2.3 cm were investigated. The size of the air gap above the sensitive volumes of the DUO was investigated in the transverse orientation to assess the anticipated magnetic field effects. Full width at half maximum (FWHM), 80-20% penumbral widths and maximum dose differences between detectors and between the presence/absence of a magnetic field were investigated. Symmetry was also assessed for investigation of profile skewness under the transverse field.

RESULTS

The penumbral widths measured by the DUO detector demonstrated good agreement with film and the M512 to within an average of 0.5 mm (within uncertainty: ±1 mm). The static inline magnetic field had minimal effect on the profiles in solid water. As expected, the lower density of solid lung meant that this material was more susceptible to demonstrating magnetic field effects in the dose deposited. The greatest penumbral narrowing due to the inline field (0.7 mm) occurred in lung. Central axis dose increase was greatest in lung (maximum: 9%). The transverse field widened penumbra, most notably in the solid lung phantom, by a maximum of 2.3 mm. The largest asymmetry due to the transverse field (4.6%) was also in solid lung. When the air gap above the DUO was filled with bolus, the dose maximum measured by the DUO was within 1.4% of film.

CONCLUSIONS

The DUO detector has been shown to be successful in accurately describing the dose changes for small field sizes to within a 200-µm resolution in an environment resembling that of an MRI-linac. The DUO measurements were in agreement with both film and the M512 measurements, and therefore the DUO was found to be an appropriate alternative to the M512, with improvement in terms of its higher spatial resolution. MARDOS provided a suitable environment for these preliminary tests before progressing to the MRI-linac.

摘要

目的

必须充分了解磁场对剂量分布和探测器功能的影响。用于研究这些磁场效应的探测器是 DUO 硅阵列探测器;在这些条件下评估了这种高空间分辨率探测器的性能。将结果与 Gafchromic EBT3 胶片进行了比较,以突出硅中的任何固有磁场效应。结果还与之前发表的 MagicPlate-512 (M512) 数据进行了比较。DUO 的空间分辨率(200 µm)优于 M512(2mm)。

方法

一种名为 Magnetic Apparatus for RaDiation Oncology Studies (MARDOS) 的永磁体与标准直线加速器 (linac) 配合使用,可使磁场相对于射线束呈横向(1.2 T)或直线(0.95 T)方向。6 MV 瓦里安 2100C 直线加速器为测量提供辐射成分。DUO 探测器有 505 个敏感体积(每个体积测量 800×40×100 µm),组织成两个正交的线性阵列。在第一个设置中,DUO 嵌入在固体水中的幻影中,然后在第二个设置中嵌入在固体肺幻影中,并放置在磁锥之间。在磁场条件下和 0 T 下比较了射束轮廓。研究了从 0.8×0.8 cm 到 2.3×2.3 cm 的小射束尺寸。研究了 DUO 敏感体积上方的空气间隙的大小,以评估预期的磁场效应。研究了全宽半最大值 (FWHM)、80-20%半影宽度以及探测器之间和存在/不存在磁场之间的最大剂量差异。还评估了横向场下的轮廓偏度以研究对称性。

结果

DUO 探测器测量的半影宽度与胶片和 M512 非常吻合,平均误差在 0.5 毫米以内(在不确定度范围内:±1 毫米)。静态直线磁场对固体水中的轮廓几乎没有影响。正如预期的那样,密度较低的固体肺意味着这种材料更容易在沉积的剂量中表现出磁场效应。由于直线场导致的最小半影变窄(0.7 毫米)发生在肺中。肺中中央轴剂量增加最大(最大:9%)。横向场使固体肺的半影变宽,最大可达 2.3 毫米。由于横向场引起的最大不对称性(4.6%)也发生在固体肺中。当 DUO 上方的空气间隙充满填充物时,DUO 测量的剂量最大值与胶片的差值在 1.4%以内。

结论

DUO 探测器已成功地以 200 µm 的分辨率准确描述了小射束尺寸的剂量变化,其环境类似于 MRI-直线加速器的环境。DUO 的测量结果与胶片和 M512 的测量结果一致,因此 DUO 是 M512 的合适替代品,其空间分辨率更高。MARDOS 为在 MRI-直线加速器之前进行这些初步测试提供了合适的环境。

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