Division of Gastroenterology and Hepatology, University of Missouri, Columbia, Missouri.
Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland, USA.
Curr Opin Gastroenterol. 2019 Sep;35(5):416-423. doi: 10.1097/MOG.0000000000000560.
Peroral endoscopic myotomy (POEM) and gastric peroral endoscopic myotomy (G-POEM) are minimally invasive endoscopic procedures for the treatment of esophageal motility disorders and refractory gastroparesis, respectively. In this review, we highlight the most recent publications on the technical aspects of POEM and G-POEM.
POEM has evolved into a standard therapeutic option in patients with all achalasia subtypes with excellent durability and safety profile. G-POEM is a novel endoscopic procedure with promising results in terms of efficacy, safety, and symptom improvement in patients with refractory gastroparesis.
POEM and G-POEM are novel endoscopic procedures. Practice patterns vary among endoscopists and procedure techniques continue to evolve. Comparative studies examining outcomes of different techniques are needed.
经口内镜下肌切开术（POEM）和胃经口内镜下肌切开术（G-POEM）分别为治疗食管动力障碍和难治性胃轻瘫的微创内镜治疗方法。在本篇综述中，我们重点介绍了 POEM 和 G-POEM 技术方面的最新出版物。
POEM 已成为所有贲门失弛缓症亚型患者的标准治疗选择，具有极好的持久性和安全性。G-POEM 是一种新的内镜治疗方法，在难治性胃轻瘫患者的疗效、安全性和症状改善方面具有良好的前景。
POEM 和 G-POEM 是新型的内镜治疗方法。术者的操作实践存在差异，并且手术技术也在不断发展。需要开展比较不同技术治疗效果的研究。
