Alpha-1 Antitrypsin Deficiency: A Predisposing Factor for the Development of Pulmonary Langerhans Cell Histiocytosis.
作者信息
Ellis Paul R, Campbell Edward J, Turner Alice M, Stockley Robert A
机构信息
Institute for Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
HerediLab Inc., Salt Lake City, Utah.
出版信息
Chronic Obstr Pulm Dis. 2019 Jul 24;6(3):206-209. doi: 10.15326/jcopdf.6.3.2019.0129.
Abstract
摘要
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Pulmonary Langerhans Cell Histiocytosis: An Update From the Pathologists' Perspective.肺朗格汉斯细胞组织细胞增多症：病理学家视角的最新进展
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A naturally occurring nonpolymerogenic mutant of alpha 1-antitrypsin characterized by prolonged retention in the endoplasmic reticulum.一种天然存在的α1-抗胰蛋白酶非聚合突变体，其特征是在内质网中滞留时间延长。
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