Human Nutrition Research Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Exercise Physiology Research Centre (CIFE), Universidad Mayor, Santiago, Chile; BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom.
Human Nutrition Research Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia.
Am J Prev Med. 2019 Aug;57(2):209-219. doi: 10.1016/j.amepre.2019.03.024. Epub 2019 Jun 25.
This study tested the hypothesis that providing personalized nutritional advice and feedback more frequently would promote larger, more appropriate, and sustained changes in dietary behavior as well as greater reduction in adiposity.
A 6-month RCT (Food4Me) was conducted in seven European countries between 2012 and 2013.
SETTING/PARTICIPANTS: A total of 1,125 participants were randomized to Lower- (n=562) or Higher- (n=563) Frequency Feedback groups.
Participants in the Lower-Frequency group received personalized nutritional advice at baseline and at Months 3 and 6 of the intervention, whereas the Higher-Frequency group received personalized nutritional advice at baseline and at Months 1, 2, 3 and 6.
The primary outcomes were change in dietary intake (at food and nutrient levels) and obesity-related traits (body weight, BMI, and waist circumference). Participants completed an online Food Frequency Questionnaire to estimate usual dietary intake at baseline and at Months 3 and 6 of the intervention. Overall diet quality was evaluated using the 2010 Healthy Eating Index. Obesity-related traits were self-measured and reported by participants via the Internet. Statistical analyses were performed during the first quarter of 2018.
At 3 months, participants in the Lower- and Higher-Frequency Feedback groups showed improvements in Healthy Eating Index score; this improvement was larger in the Higher-Frequency group than the Lower-Frequency group (Δ=1.84 points, 95% CI=0.79, 2.89, p=0.0001). Similarly, there were greater improvements for the Higher- versus Lower-Frequency group for body weight (Δ= -0.73 kg, 95% CI= -1.07, -0.38, p<0.0001), BMI (Δ= -0.24 kg/m, 95% CI= -0.36, -0.13, p<0.0001), and waist circumference (Δ= -1.20 cm, 95% CI= -2.36, -0.04, p=0.039). However, only body weight and BMI remained significant at 6 months.
At 3 months, higher-frequency feedback produced larger improvements in overall diet quality as well as in body weight and waist circumference than lower-frequency feedback. However, only body weight and BMI remained significant at 6 months.
This study is registered at www.clinicaltrials.gov NCT01530139.
本研究旨在验证以下假设，即更频繁地提供个性化营养建议和反馈，将促进膳食行为的更大、更适当和更持续的改变，并更大程度地减少肥胖。
这是一项于 2012 年至 2013 年在七个欧洲国家进行的为期 6 个月的随机对照试验（Food4Me）。
设置/参与者：共有 1125 名参与者被随机分配到低（n=562）或高（n=563）频率反馈组。
低频率组的参与者在基线和干预的第 3 和第 6 个月接受个性化营养建议，而高频率组在基线和第 1、2、3 和 6 个月接受个性化营养建议。
主要结局指标是膳食摄入（食物和营养素水平）和肥胖相关特征（体重、BMI 和腰围）的变化。参与者完成了在线食物频率问卷，以估计基线和干预的第 3 和第 6 个月的常规膳食摄入量。使用 2010 年健康饮食指数评估整体饮食质量。肥胖相关特征由参与者通过互联网自行测量和报告。统计分析于 2018 年第一季度进行。
在 3 个月时，低频率和高频率反馈组的参与者的健康饮食指数评分均有所提高；高频率组的改善大于低频率组（Δ=1.84 分，95%CI=0.79，2.89，p=0.0001）。同样，高频率组相对于低频率组，体重（Δ=-0.73kg，95%CI=-1.07，-0.38，p<0.0001）、BMI（Δ=-0.24kg/m，95%CI=-0.36，-0.13，p<0.0001）和腰围（Δ=-1.20cm，95%CI=-2.36，-0.04，p=0.039）的改善更大。然而，只有体重和 BMI 在 6 个月时仍具有统计学意义。
在 3 个月时，高频率反馈在整体饮食质量以及体重和腰围方面产生的改善大于低频率反馈。然而，只有体重和 BMI 在 6 个月时仍具有统计学意义。
本研究在 www.clinicaltrials.gov 注册，编号为 NCT01530139。
