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超声心动图预测功能性三尖瓣反流三尖瓣环成形术修复失败的指标。

Echocardiographic Predictors of Tricuspid Ring Annuloplasty Repair Failure for Functional Tricuspid Regurgitation.

机构信息

Department of Anesthesiology, Rhode Island Hospital, Providence, RI.

Cardiology Associates of Schenectady, Nishayuna, NY.

出版信息

J Cardiothorac Vasc Anesth. 2019 Oct;33(10):2624-2633. doi: 10.1053/j.jvca.2019.05.043. Epub 2019 May 30.

Abstract

OBJECTIVE

Significant tricuspid regurgitation (TR) recurs after tricuspid valve repair of functional TR in 15% to 20% within the first year, and 30% to 70% within 5 years. Prior investigations report leaflet tethering, and not tricuspid valve annular diameter (TVAD), as predictive of recurrent TR. The authors hypothesize that pre-repair TVAD is predictive of repair failure for functional TR.

PARTICIPANTS

Fifty-four patients with functional TR scheduled for left heart surgery and tricuspid valve repair with ring annuloplasty.

DESIGN

Retrospective study design. Pre- and post-repair transthoracic and intraoperative transesophageal echocardiographic data included left and right ventricular functions, tricuspid leaflet tethering height, TVAD, and TR severity. Successful repair was defined as ≤2+ TR.

SETTING

Tertiary care medical center.

INTERVENTIONS

None.

MEASUREMENTS

Forty-five patients had a successful repair and 9 did not. Preoperative and intraoperative TVAD in diastole (TVADdiast) ≥4.2 cm, and preoperative systole (TVADsyst) ≥3.7 cm, but not leaflet tethering, were predictive of repair failure. Right ventricular (RV) width >4.88 cm was associated with repair failure. Neither pre- nor post-repair pulmonary artery systolic pressures (PASP) were predictors of repair failure. However, PASP did not change nor did RV function improve in the nonsuccessful repair group.

CONCLUSION

For patients with functional TR undergoing primary left heart surgery, preoperative TVAD (systole and diastole), RV width, and postoperative RV function were predictors of repair outcome. Earlier TV repair and optimizing right heart function may improve repair outcome.

摘要

目的

在功能三尖瓣反流(TR)修复后的最初 1 年内,约有 15%至 20%的患者会出现明显的三尖瓣反流复发,而在 5 年内,这一比例则上升至 30%至 70%。先前的研究报告指出,瓣叶牵拉而不是三尖瓣环直径(TVAD)与复发性 TR 相关。作者假设术前 TVAD 可预测功能性 TR 的修复失败。

参与者

54 例功能性 TR 患者,拟行左心手术及三尖瓣环成形术修复。

设计

回顾性研究设计。术前和术后经胸超声心动图和术中经食管超声心动图数据包括左、右心室功能、三尖瓣瓣叶牵拉高度、TVAD 和 TR 严重程度。成功修复定义为≤2+TR。

地点

三级医疗中心。

干预措施

无。

测量

45 例患者修复成功,9 例患者修复失败。术前和术中舒张期 TVAD(TVADdiast)≥4.2cm 和术前收缩期 TVAD(TVADsyst)≥3.7cm,但瓣叶牵拉不预测修复失败。右心室(RV)宽度>4.88cm 与修复失败相关。术前和术后肺动脉收缩压(PASP)均不是修复失败的预测因素。然而,在修复失败的患者中,PASP 并未改变,RV 功能也未改善。

结论

对于功能性 TR 患者,行初次左心手术时,术前 TVAD(收缩期和舒张期)、RV 宽度和术后 RV 功能是修复结果的预测因素。早期进行 TV 修复并优化右心功能可能会改善修复结果。

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