Piscitani Luca, Sirolli Vittorio, Di Vito Roberto, Muscianese Patrizia, Brummer Uwe Florian Manfred, Di Liberato Lorenzo, Bonomini Mario
Dipartimento di Medicina e Scienze dell'Invecchiamento, Università "G. d'Annunzio" di Chieti-Pescara.
Dipartimento di Medicina e Scienze dell'Invecchiamento, Università "G. d'Annunzio" di Chieti-Pescara and UOC Nefrologia e Dialisi, Ospedale SS. Annunziata, Chieti, Italia.
G Ital Nefrol. 2019 Jun 11;36(3):2019-vol3.
Calcific uremic arteriolopathy, also known as calciphylaxis (CUA), is a rare and potentially fatal condition that occurs in 1-4% of the population with chronic renal failure, most often on dialysis treatment. The pathogenesis is not yet clear although several hypotheses have been advanced, most importantly the alteration of the calcium phosphorus metabolism. Administration of sodium thiosulfate (STS) is the emerging therapy. Below, we report the case of an elderly chronic kidney patient on conservative therapy suffering from CUA who has been successfully treated with STS.
钙化性尿毒症小动脉病，也称为钙化防御（CUA），是一种罕见且可能致命的疾病，发生于1%-4%的慢性肾衰竭患者中，最常发生在接受透析治疗的患者身上。尽管已经提出了几种假说，但其发病机制尚不清楚，其中最重要的是钙磷代谢的改变。硫代硫酸钠（STS）给药是一种新兴的治疗方法。下面，我们报告一例接受保守治疗的老年慢性肾脏病患者患有钙化防御，经硫代硫酸钠成功治疗的病例。
