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[U-120回旋加速器产生的治疗性快中子束的相对生物效应特性]

[Characteristics of the RBE of a therapeutic beam of fast neutrons from a U-120 cyclotron].

作者信息

Gul'ko G M, Bezdrobnaia L K, Chernichenko V A

出版信息

Radiobiologiia. 1988 Jan-Feb;28(1):73-5.

PMID:3125563
Abstract

RBE of a therapeutic neutron beam obtained at the U-120 Cyclotron by a 9 Be(d, n)10B reaction (13.6 MeV deuterons) was determined. X-radiation of 180 kW was used as a standard. As estimated by the test of 30-day death of rats subjected to whole-body irradiation, RBE of fast neutrons varied from 3.44 to 2.03 within the dose range from 0.4 to 2.7 Gy. As estimated by the growth inhibition (during 60 days) of Guerin's carcinoma inoculated in rat femur RBE varied from 4.68 to 2.76 within the dose range from 2.3 to 12.0 Gy.

摘要

测定了在U - 120回旋加速器上通过9Be(d, n)10B反应(13.6兆电子伏特氘核)获得的治疗性中子束的相对生物效应(RBE)。使用180千瓦的X射线辐射作为标准。通过对接受全身照射的大鼠进行30天死亡试验估计,在0.4至2.7戈瑞的剂量范围内,快中子的RBE在3.44至2.03之间变化。通过对接种在大鼠股骨中的格林氏癌生长抑制(60天内)估计,在2.3至12.0戈瑞的剂量范围内,RBE在4.68至2.76之间变化。

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