什么是兴奋/抑制以及它是如何被调节的？一个大象与智者的例子。
What Is Excitation/Inhibition and How Is It Regulated? A Case of the Elephant and the Wisemen.
作者信息
He Hai-Yan, Cline Hollis T
机构信息
The Scripps Research Institute, La Jolla, CA, USA.
出版信息
J Exp Neurosci. 2019 Jun 23;13:1179069519859371. doi: 10.1177/1179069519859371. eCollection 2019.
Abstract
The balance between excitation and inhibition in neuronal circuits has drawn more and more attention in recent years, due to its proposed multifaceted functions in the normal neural circuit as well as its potential roles in the etiology of many neurological disorders. Here, we discuss the importance of clearly defining excitation/inhibition by experimental measurements and the implications of some recent studies to our understanding of the regulation of excitation/inhibition at the neuronal level.
摘要
近年来，神经元回路中兴奋与抑制之间的平衡受到了越来越多的关注，这是因为它在正常神经回路中具有多方面的功能，以及在许多神经疾病的病因学中可能发挥的作用。在此，我们讨论通过实验测量明确界定兴奋/抑制的重要性，以及一些近期研究对我们理解神经元水平上兴奋/抑制调节的启示。
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