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表现为咽旁肿块的Castleman病:一例报告并文献复习

Castleman Disease Presenting as a Parapharyngeal Mass: A Case Report and Review of the Literature.

作者信息

Choi David Leo, Brannock Kristina, Tang Alice L

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

出版信息

Clin Med Insights Case Rep. 2019 Jun 24;12:1179547619853799. doi: 10.1177/1179547619853799. eCollection 2019.

DOI:10.1177/1179547619853799
PMID:31258339
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6591652/
Abstract

OBJECTIVES

Masses in the parapharyngeal space often pose a diagnostic and therapeutic challenge due to an inaccessible location for biopsy and proximity to critical neurovascular structures of the neck. The aims of this study are to describe a rare case of Castleman disease (CD) presenting in the parapharyngeal space.

METHODS

Case report of a 38-year-old male presenting to a tertiary care center and literature review.

RESULTS & CONCLUSIONS: The parapharyngeal space is an unusual location for CD. Surgeons, radiologists, and pathologists must be aware of this disease entity within the differential diagnosis to provide appropriate perioperative counseling for patients.

摘要

目的

由于咽旁间隙的肿物位置难以进行活检且靠近颈部重要的神经血管结构,因此对其进行诊断和治疗颇具挑战。本研究旨在描述1例罕见的发生于咽旁间隙的Castleman病(CD)病例。

方法

对1例就诊于三级医疗中心的38岁男性患者进行病例报告并进行文献复习。

结果与结论

CD发生于咽旁间隙实属罕见。外科医生、放射科医生和病理科医生在鉴别诊断时必须了解这一疾病实体,以便为患者提供适当的围手术期咨询。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/073e/6591652/b8c526dfefbf/10.1177_1179547619853799-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/073e/6591652/0b20cdfa9e61/10.1177_1179547619853799-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/073e/6591652/21bab3a4298c/10.1177_1179547619853799-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/073e/6591652/b8c526dfefbf/10.1177_1179547619853799-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/073e/6591652/0b20cdfa9e61/10.1177_1179547619853799-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/073e/6591652/21bab3a4298c/10.1177_1179547619853799-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/073e/6591652/b8c526dfefbf/10.1177_1179547619853799-fig3.jpg

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本文引用的文献

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Epidemiology of Castleman Disease.卡斯特曼病的流行病学
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Update and new approaches in the treatment of Castleman disease.卡斯特曼病治疗的最新进展与新方法
J Blood Med. 2016 Aug 3;7:145-58. doi: 10.2147/JBM.S60514. eCollection 2016.
3
Preoperative diagnosis of vagal and sympathetic cervical schwannomas based on radiographic findings.基于影像学表现的迷走神经和交感神经颈 schwannomas 的术前诊断。
Case Rep Ophthalmol Med. 2020 Jan 3;2020:1012759. doi: 10.1155/2020/1012759. eCollection 2020.
J Neurosurg. 2017 Mar;126(3):690-697. doi: 10.3171/2016.1.JNS151763. Epub 2016 Apr 22.
4
Clinical and laboratory characterization of 114 cases of Castleman disease patients from a single centre: paraneoplastic pemphigus is an unfavourable prognostic factor.单中心 114 例 Castleman 病患者的临床和实验室特征:副肿瘤天疱疮是一个不利的预后因素。
Br J Haematol. 2015 Jun;169(6):834-42. doi: 10.1111/bjh.13378. Epub 2015 Mar 30.
5
Castleman disease of the neck: CT and MR imaging findings.颈部Castleman病:CT与MR成像表现
Eur J Radiol. 2014 Nov;83(11):2041-50. doi: 10.1016/j.ejrad.2014.08.013. Epub 2014 Sep 2.
6
Use of a claims database to characterize and estimate the incidence rate for Castleman disease.利用索赔数据库来描述和估计卡斯特曼病的发病率。
Leuk Lymphoma. 2015 May;56(5):1252-60. doi: 10.3109/10428194.2014.953145. Epub 2014 Sep 29.
7
Monoclonality and cytogenetic abnormalities in hyaline vascular Castleman disease.透明血管型Castleman病中的单克隆性和细胞遗传学异常。
Mod Pathol. 2014 Jun;27(6):823-31. doi: 10.1038/modpathol.2013.202. Epub 2013 Nov 8.
8
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