Wang Xin, Chen Yong-Chao, Pan Hong-Guang, Teng Yi-Shu
Department of Otorhinolaryngology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
Department of Otorhinolaryngology, Shenzhen Children's Hospital, China Medical University, Shenzhen, Guangdong, China.
Ear Nose Throat J. 2023 Nov 24:1455613231214643. doi: 10.1177/01455613231214643.
The Castleman Disease (CD), also recognized as giant lymph node hyperplasia or vascular follicular lymphoid hyperplasia, is an infrequent lymphoproliferative disorder with substantial clinical variability. Parapharyngeal location of this disease is very rare and in pediatric population it is even rarer. This article presents a case of Unicentric CD (hyaline vascular type) in an 8-year-old female, where the disease was localized within the parapharyngeal space. Clinical manifestations were limited to the presence of a local mass, with no other specific symptoms observed. Laboratory assessments revealed no significant abnormalities. She underwent surgery using a cervical-parotid approach and experienced a good postoperative recovery. Histopathological analysis confirmed the diagnosis. This case underscores the need for a comprehensive evaluation and consideration of uncommon etiologies in the assessment of parapharyngeal masses, even in pediatric patients.
Castleman病（CD），也被认为是巨大淋巴结增生症或血管滤泡性淋巴组织增生症，是一种临床变异性较大的罕见淋巴增生性疾病。该病发生于咽旁部位非常罕见，在儿童群体中更为罕见。本文介绍了一例8岁女性的单中心Castleman病（透明血管型），病变局限于咽旁间隙。临床表现仅为局部肿块，未观察到其他特异性症状。实验室检查未发现明显异常。她接受了颈腮腺入路手术，术后恢复良好。组织病理学分析确诊了该病。该病例强调，即使在儿科患者中，评估咽旁肿块时也需要进行全面评估并考虑罕见病因。
