Celik H, Guldiken S, Celik O, Taymez F, Dagdeviren N, Tuğrul A
Trakya University - Division of Endocrinology and Metabolism, Department of Internal Medicine, Edirne, Turkey.
Acıbadem University - Division of Endocrinology and Metabolism, Department of Internal Medicine, Edirne, Turkey.
Acta Endocrinol (Buchar). 2016 Jan-Mar;12(1):14-18. doi: 10.4183/aeb.2016.14.
Data about iodine status in pregnant women in Turkey is not sufficient. We aimed to determine the iodine status, goiter prevalence, iodized salt consumption among first trimester pregnant women living in Edirne.
Cross-sectional study was performed on pregnant women living in Edirne.
A total of 275 pregnant women in their first trimester were examined regarding iodized salt use, median urinary iodine concentration (UIC), presence or absence of goitre and thyroid function. Goitre status was determined by palpation. Participants filled out a questionnaire, which included questions regarding sociodemographic features, iodized salt consumption, knowledge, and behavior regarding iodine deficiency. UIC was measured using colorimetric method based on Sandell-Kolthoff reaction. Thyroid hormones and TSH were measured by chemiluminescence immunoassays.
While the proportion of iodized salt use was 96.6%, UIC was below 150 μg/L in 88.4 % of the women. The median UIC was 77 μg/L, indicating insufficient iodine intake. Total goitre rate was 19.3%.
Our study shows that iodine deficiency is a serious problem among pregnant women in Edirne. We suggest that pregnant women living in Edirne should be supplemented by iodine-containing preparations in addition to iodized salt.
土耳其孕妇碘状况的数据并不充分。我们旨在确定居住在埃迪尔内的孕早期妇女的碘状况、甲状腺肿患病率及碘盐食用情况。
对居住在埃迪尔内的孕妇进行横断面研究。
共检查了275名孕早期妇女的碘盐使用情况、尿碘中位数浓度（UIC）、是否存在甲状腺肿及甲状腺功能。通过触诊确定甲状腺肿状况。参与者填写了一份问卷，其中包括有关社会人口学特征、碘盐食用情况、碘缺乏相关知识和行为的问题。基于桑德尔-科尔托夫反应，采用比色法测量UIC。通过化学发光免疫分析法测量甲状腺激素和促甲状腺激素（TSH）。
碘盐使用率为96.6%，但88.4%的妇女UIC低于150μg/L。UIC中位数为77μg/L，表明碘摄入不足。甲状腺肿总患病率为19.3%。
我们的研究表明，碘缺乏是埃迪尔内孕妇中的一个严重问题。我们建议，除碘盐外，居住在埃迪尔内的孕妇还应补充含碘制剂。
