Koh Don, Tan Shi Ming, Tan Andrew Hwee Chye
Andrew Tan, Department of Orthopaedic Surgery, Singapore General Hospital, Singapore 169856, Singapore.
World J Orthop. 2019 Jun 18;10(6):255-261. doi: 10.5312/wjo.v10.i6.255.
Surgical site infections following anterior cruciate ligament (ACL) reconstruction are an uncommon but potentially devastating complication. In this study, we present an unusual case of recurrent infection of the knee after an ACL reconstruction, and discuss the importance of accurate diagnosis and appropriate management, including the issue of graft preservation versus removal.
A 33-year-old gentleman underwent ACL reconstruction using a hamstring tendon autograft with suspensory Endobutton fixation to the distal femur and an interference screw fixation to the proximal tibia. Four years after ACL reconstruction, he developed an abscess over the proximal tibia and underwent incision and drainage. Remnant suture material was found at the base of the abscess and was removed. Five years later, he re-presented with a lateral distal thigh abscess that encroached the femoral tunnel. He underwent incision and drainage of the abscess which was later complicated by a chronic discharging sinus. Repeated magnetic resonance imaging revealed a fistulous communication between the lateral thigh wound extending toward the femoral tunnel with suggestion of osteomyelitis. Decision was made for a second surgery and the patient was counselled about the need for graft removal should there be intra-articular involvement. Knee arthroscopy revealed the graft to be intact with no evidence of intra-articular involvement. As such, the decision was made to retain the ACL graft. Re-debridement, excision of the sinus tract and removal of Endobutton was also performed in the same setting. Joint fluid cultures did not grow bacteria. However, tissue cultures from the femoral tunnel abscess grew Enterobacter cloacae complex, similar to what grew in tissue cultures from the tibial abscess five years earlier. In view of the recurrent and indolent nature of the infection, antibiotic therapy was escalated from Clindamycin to Ertapenem. He completed a six-week course of intravenous antibiotics and has been well for six months since surgery, with excellent knee function and no evidence of any further infection.
Prompt and accurate diagnosis of surgical site infection following ACL reconstruction, including the exclusion of intra-articular involvement, is important for timely and appropriate treatment. Arthroscopic debridement and removal of implant with graft preservation, together with a course of antibiotics, is a suitable treatment option for extra-articular knee infections following ACL reconstruction.
前交叉韧带(ACL)重建术后手术部位感染是一种罕见但可能具有毁灭性的并发症。在本研究中,我们报告了一例ACL重建术后膝关节反复感染的罕见病例,并讨论了准确诊断和适当处理的重要性,包括移植物保留与移除的问题。
一名33岁男性接受了ACL重建手术,采用自体腘绳肌腱移植,股骨远端使用悬吊式Endobutton固定,胫骨近端使用挤压螺钉固定。ACL重建术后四年,他在胫骨近端出现脓肿,并接受了切开引流。在脓肿底部发现了残留的缝线材料并予以移除。五年后,他再次出现大腿远端外侧脓肿,累及股骨隧道。他接受了脓肿切开引流,随后出现慢性流脓性窦道并发症。反复磁共振成像显示大腿外侧伤口与股骨隧道之间存在瘘管相通,并提示存在骨髓炎。决定进行二次手术,并告知患者如果存在关节内受累则需要移除移植物。膝关节镜检查显示移植物完整,无关节内受累迹象。因此,决定保留ACL移植物。同时进行了再次清创、窦道切除和Endobutton移除。关节液培养未培养出细菌。然而,股骨隧道脓肿的组织培养生长出阴沟肠杆菌复合体,与五年前胫骨脓肿的组织培养结果相似。鉴于感染的反复性和顽固性,抗生素治疗从克林霉素升级为厄他培南。他完成了为期六周的静脉抗生素治疗,自手术以来六个月情况良好,膝关节功能良好,无任何进一步感染的迹象。
ACL重建术后手术部位感染的及时准确诊断,包括排除关节内受累,对于及时恰当的治疗很重要。关节镜清创、移除植入物并保留移植物,同时联合抗生素治疗,是ACL重建术后膝关节关节外感染的合适治疗选择。