Alsaleem Mahdi, Saadeh Lina, Kumar Vasantha H S, Wilding Gregory E, Miller Lorin, Mathew Bobby
University at Buffalo, State University of New York, Buffalo, NY, USA.
Glob Pediatr Health. 2019 Jun 21;6:2333794X19857415. doi: 10.1177/2333794X19857415. eCollection 2019.
There is variability in practice among care providers on feeding infants admitted with neonatal hypoglycemia (NH) for parenteral dextrose. We compared clinical outcomes in infants who were fed (NH-Fed) and hypoglycemic infants who were kept nothing per os (NPO) (NH-NPO) at the time of initiation of intravenous (IV) dextrose. We performed a retrospective review of all newborn infants admitted to the neonatal intensive care unit with NH for IV dextrose. Infants were grouped as per the feeding approach at initiation of IV dextrose: NH-Fed or NH-NPO infants. We found that infants in the NH-Fed group had lower maximum glucose infusion rate, less duration of glucose infusion therapy compared with the NH-NPO group, and significantly less number of days of hospital stay compared with the NH-NPO group (5.87 ± 1.4 days vs 4.9 ± 1.4 days, < .006). In conclusion, feeding infants with hypoglycemia who require IV dextrose offers tangible benefits of shorter duration of parenteral dextrose and shorter length of hospitalization.
在为因新生儿低血糖(NH)入院的婴儿输注胃肠外葡萄糖时,护理人员的操作存在差异。我们比较了开始静脉输注葡萄糖时已接受喂养的婴儿(NH - 喂养组)和禁食的低血糖婴儿(NH - 非禁食组)的临床结局。我们对所有因NH入住新生儿重症监护病房接受静脉输注葡萄糖的新生儿进行了回顾性研究。根据开始静脉输注葡萄糖时的喂养方式,将婴儿分为NH - 喂养组或NH - 非禁食组。我们发现,与NH - 非禁食组相比,NH - 喂养组婴儿的最大葡萄糖输注速率更低,葡萄糖输注治疗持续时间更短,住院天数也显著更少(5.87±1.4天对4.9±1.4天,P<0.006)。总之,为需要静脉输注葡萄糖的低血糖婴儿提供喂养可带来胃肠外葡萄糖输注持续时间缩短和住院时间缩短的切实益处。