头颈部鳞状细胞癌类器官的预测潜能。
Predictive Potential of Head and Neck Squamous Cell Carcinoma Organoids.
机构信息
Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.
Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
出版信息
Cancer Discov. 2019 Jul;9(7):828-830. doi: 10.1158/2159-8290.CD-19-0527.
In this issue of , Driehuis and colleagues establish culture conditions for the rapid, efficient, and long-term expansion of healthy human oral mucosa and head and neck squamous cell carcinoma (HNSCC) tumor organoids. The HNSCC tumor organoids provide a functional platform for analyzing tumor cell phenotype, tumorigenic potential, and drug and radiotherapy response, and they have a potential role in clinical decision-making..
本期 中，Driehuis 及其同事为快速、高效、长期扩增健康人口腔黏膜和头颈部鳞状细胞癌（HNSCC）肿瘤类器官建立了培养条件。HNSCC 肿瘤类器官为分析肿瘤细胞表型、致瘤潜能、药物和放疗反应提供了一个功能平台，它们在临床决策中有潜在的作用。
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