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老年结直肠癌患者——术后并发症的易感人群

Elderly Patients with Colorectal Cancer - A Predisposed Category for Postoperative Complications.

作者信息

Etele Élthes Előd, Sala Daniela, Dénes Márton, Cozlea Alexandra, Darie Ruxandra, Török Árpád

出版信息

Chirurgia (Bucur). 2019 May-Jun;114(3):331-342. doi: 10.21614/chirurgia.114.3.331.

Abstract

Colorectal cancer (CRC) is among the leading causes of cancer-related deaths around the world. Elderly patients are often considered as a high-risk category of patients, predisposed for postoperative complications. Materials and methods: 138 patients aged over 75 years and diagnosed with colorectal cancer were retrospectively reviewed. Patients were divided in two groups, as follows: Study Group including patients who developed postoperative complications, and Control Group including patients without problems in the postoperative period. There were compared clinical, preoperative, surgical, postoperative and oncological data. The aim of study was to determine possible risk factors for short-term postoperative complications and analyze of the influence of postoperative complications on survival. Risk factors as male gender, obesity, heart failure, diabetes type II, severe anemia, low total protein level, ASA III-IV classification, emergency surgery, prolonged surgical intervention, increased intraoperative blood loss, prolonged hospital stay, distal localization of tumors, TNM stages III-IV, surgery for digestive cancer and non-cancerous major abdominal surgery in the medical history were identified. Conclusion: The surgical treatment of colorectal cancer in the aging population still remains a challenge, these category of patients should benefit of special attention in order to ensure a chance to minimize or avoid these complications.

摘要

结直肠癌(CRC)是全球癌症相关死亡的主要原因之一。老年患者通常被视为高危患者群体,易发生术后并发症。材料与方法:回顾性分析138例年龄超过75岁且诊断为结直肠癌的患者。患者分为两组,如下:研究组包括发生术后并发症的患者,对照组包括术后无问题的患者。比较了临床、术前、手术、术后和肿瘤学数据。研究目的是确定术后短期并发症的可能危险因素,并分析术后并发症对生存的影响。确定的危险因素包括男性、肥胖、心力衰竭、II型糖尿病、严重贫血、总蛋白水平低、ASA III-IV级分类、急诊手术、手术时间延长、术中失血增加、住院时间延长、肿瘤远端定位、TNM III-IV期、消化道癌症手术以及病史中有非癌性腹部大手术。结论:老年人群结直肠癌手术治疗仍然是一项挑战,这类患者应得到特别关注,以确保有机会尽量减少或避免这些并发症。

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