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肾衰竭、休克与起搏器夺获失败:一例氟卡尼中毒病例

Renal failure, shock, and loss of pacemaker capture: A case of flecainide intoxication.

作者信息

Heldens M, van der Nat G A M, Melman P G

机构信息

Intensive Care Unit, Sydney Adventist Hospital, Sydney, Australia.

出版信息

Neth J Med. 2019 Jun;77(5):189-192.

PMID:31264585
Abstract

Flecainide intoxication is a severe intoxication that can lead to cardiogenic shock. We report on a 68-year-old female patient, who presented with a flecainide intoxication in the setting of renal failure. She was managed with invasive supportive therapy at the ICU and infusion of sodium bicarbonate and intravenous lipid emulsion (ILE, intralipid 20%), after which she made a complete recovery.

摘要

氟卡尼中毒是一种可导致心源性休克的严重中毒。我们报告一例68岁女性患者,她在肾衰竭情况下出现氟卡尼中毒。她在重症监护病房接受了有创支持治疗,并输注了碳酸氢钠和静脉注射脂质乳剂(ILE,20% 英脱利匹特),之后完全康复。

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Renal failure, shock, and loss of pacemaker capture: A case of flecainide intoxication.肾衰竭、休克与起搏器夺获失败:一例氟卡尼中毒病例
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引用本文的文献

1
Case Files from the University of California San Diego Medical Toxicology Fellowship: Neonatal Flecainide Toxicity from an Accidental Dosing Error.加利福尼亚大学圣地亚哥分校医学毒理学奖学金项目病例档案:因意外用药剂量错误导致的新生儿氟卡尼中毒
J Med Toxicol. 2024 Jul 11;20(3):314-323. doi: 10.1007/s13181-024-01018-9.
2
Flecainide causing elevated capture thresholds on pacemaker implantation.氟卡尼导致起搏器植入时捕获阈值升高。
BMJ Case Rep. 2024 Mar 21;17(3):e259098. doi: 10.1136/bcr-2023-259098.
3
First Case of Acute Poisoning with Amiodarone and Flecainide in Attempted Suicide Successfully Managed with Lipid Emulsion Therapy in the Emergency Department: Case Report and Literature Review.
急诊科应用脂质乳剂疗法成功救治胺碘酮和氟卡尼急性中毒自杀未遂首例:病例报告及文献综述
Healthcare (Basel). 2021 Jun 4;9(6):671. doi: 10.3390/healthcare9060671.
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Lipid emulsion inhibits the vasodilation induced by a toxic dose of amlodipine in isolated rat aortae.脂乳剂抑制了阿洛地平中毒剂量诱导的离体大鼠主动脉舒张。
Int J Med Sci. 2019 Nov 9;16(12):1621-1630. doi: 10.7150/ijms.38502. eCollection 2019.