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用碳酸氢盐和脂质乳剂治疗氯喹过量后发生的心搏骤停。

Cardiac arrest following chloroquine overdose treated with bicarbonate and lipid emulsion.

作者信息

Bethlehem C, Jongsma M, Korporaal-Heijman J, Yska J P

机构信息

Department of Intensive Care, ZGT Hospital, Almelo, the Netherlands.

出版信息

Neth J Med. 2019 Jun;77(5):186-188.

PMID:31264584
Abstract

We describe a 27-year-old female with repeated episodes of pulseless electrical activity due to intoxication with a substance that was unidentified at presentation. Severe QRS widening was observed and empiric treatment with sodium bicarbonate and intravenous lipid emulsion was administered. In this case, intraosseous administration of lipid emulsion failed to improve haemodynamic parameters, suggesting that this dose remained in the bone marrow compartment. We recommend that physicians become aware of this possibility and to avoid intraosseous administration of lipid emulsion.

摘要

我们描述了一名27岁女性,因摄入一种就诊时未明确的物质而反复出现无脉性电活动。观察到严重的QRS波增宽,并给予碳酸氢钠和静脉注射脂质乳剂进行经验性治疗。在该病例中,经骨内给予脂质乳剂未能改善血流动力学参数,提示该剂量仍留在骨髓腔室中。我们建议医生了解这种可能性,并避免经骨内给予脂质乳剂。

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