1 Wendy Novak Diabetes Center, University of Louisville, Norton Children's Hospital, Louisville, Kentucky.
2 Department of Health and Sport Sciences, University of Louisville, Louisville, Kentucky.
Diabetes Technol Ther. 2019 Jul;21(7):406-408. doi: 10.1089/dia.2019.0048.
For someone managing type 1 diabetes, understanding their body's glucose response to physical activity could aid in effectively addressing nocturnal hypoglycemia. The purpose of this investigation was to examine the acute temporal associations between blood glucose and measures of moderate-vigorous physical activity (MVPA) through an accelerometer. Ten adolescent athletes with type 1 diabetes wore an accelerometer and continuous glucose monitor (CGM) consecutively for a minimum of 2 weeks. Physical activity was analyzed according to intensity indicating time spent in light, moderate, and vigorous intensities. Hypoglycemic episodes were defined as two successive CGM readings <70 mg/dL, at 5-min intervals, with an episode ending with at least two CGM readings >70 mg/dL. Incidence of nocturnal hypoglycemia occurred during 29% of the nights measured with an average duration of 52.33 ± 41.04 min. When combining total minutes of moderate and vigorous intensities a significant difference was observed between combined MVPA and number of nocturnal hypoglycemic episodes (62.92 min vs. 49 episodes, = 0.02). Moderate intensity activity alone was not significant in predicting hypoglycemic events or duration. Vigorous intensity physical activity was a significant predictor of nocturnal hypoglycemia after controlling for sedentary and light intensity minutes, age, and gender ( = 0.21, = 0.01) with an average time of 26 min of vigorous intensity. Engaging in vigorous intensity physical activity increased the risk of prolonged nocturnal hypoglycemia in adolescent athletes with type 1 diabetes. Incorporating accelerometers into patient care could prove beneficial when making further recommendations for athletes.
对于 1 型糖尿病患者来说，了解身体对体力活动的血糖反应有助于有效解决夜间低血糖问题。本研究旨在通过加速度计检查血糖与中高强度体力活动（MVPA）测量之间的急性时间关联。10 名患有 1 型糖尿病的青少年运动员连续佩戴加速度计和连续血糖监测仪（CGM）至少 2 周。根据强度分析体力活动，指示轻、中、高强度的时间。低血糖发作定义为两次连续 CGM 读数<70mg/dL，间隔 5 分钟，发作结束时至少有两次 CGM 读数>70mg/dL。夜间低血糖发生在测量的 29%的夜间，平均持续时间为 52.33±41.04 分钟。当将中高强度的总分钟数结合起来时，中度和高强度的 MVPA 与夜间低血糖发作次数之间存在显著差异（62.92 分钟与 49 次发作， = 0.02）。单独进行中等强度活动并不能显著预测低血糖事件或持续时间。在控制久坐和低强度分钟数、年龄和性别后，剧烈强度体力活动是夜间低血糖的显著预测因素（ = 0.21， = 0.01），平均剧烈强度时间为 26 分钟。在 1 型糖尿病青少年运动员中，进行剧烈强度体力活动会增加夜间低血糖延长的风险。将加速度计纳入患者护理中可能有助于在为运动员提供进一步建议时发挥作用。
