Yamamoto Y, Kimoto M, Kasai Y, Seo Y, Nagano H, Shimizu H, Mure T, Iwamoto S, Nobutou H, Sano K
Dept. of Surgery, Kawasaki Medical School.
Gan To Kagaku Ryoho. 1988 Mar;15(3):519-22.
A 57-year-old female was admitted for advanced ascending colon cancer with a solitary pulmonary metastasis measuring 1.5 cm in diameter. As laparotomy revealed an absolute noncurable tumor of stage V (H0, p2, s2 n1 (+], palliative right hemicolectomy was performed. A pathological diagnosis of well differentiated adenocarcinoma was made postoperatively. A daily dose of 400 mg of UFT was given orally. After 8 months, plain chest film and tomography revealed a reduction in the size of the pulmonary metastasis to 1.0 cm in diameter. The metastatic lung tumor was controlled for a period of 1 year and 9 months. It was suggested that UFT was rather effective for pulmonary metastasis from colon cancer.
一名57岁女性因升结肠癌晚期伴直径1.5厘米的孤立性肺转移入院。剖腹手术显示为绝对无法治愈的Ⅴ期肿瘤(H0,p2,s2,n1(+)),遂行姑息性右半结肠切除术。术后病理诊断为高分化腺癌。口服UFT,每日剂量400毫克。8个月后,胸部平片和断层扫描显示肺转移灶大小缩小至直径1.0厘米。转移性肺肿瘤得到控制达1年9个月。提示UFT对结肠癌肺转移相当有效。