Ahn Kwangjin, Hwang Gyu Yel, Kim Young Keun, Kim Hyo Youl, Jeong Hye Ran, Hong Jun Sung, Uh Young
Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju Severance Christian Hospital, Wonju, Korea.
Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju Severance Christian Hospital, Wonju, Korea.
Infect Chemother. 2019 Jun;51(2):177-182. doi: 10.3947/ic.2019.51.2.177.
Carbapenemase-producing (CPE) is an important and increasing threat to global health. From July to September 2017, 20 inpatients at a tertiary care hospital in Korea were either colonized or infected with carbapenem-resistant strains. All of isolates co-produced and carbapenemase genes and shared ≥88% clonal relatedness on the basis of a cladistic calculation of the distribution of pulsed-field gel electrophoresis patterns. Rapid detection of CPE is one of the most important factors to prevent CPE dissemination because it takes long time for CPE to become negative.
产碳青霉烯酶（CPE）对全球健康构成了重大且日益严重的威胁。2017年7月至9月，韩国一家三级护理医院的20名住院患者被耐碳青霉烯菌株定植或感染。所有分离株均共同产生碳青霉烯酶基因，并且根据脉冲场凝胶电泳图谱分布的分支计算，克隆相关性≥88%。快速检测CPE是预防CPE传播的最重要因素之一，因为CPE转为阴性需要很长时间。
