携带毒力相关蛋白A基因导致成年美洲驼发生脓性肉芽肿性肠炎和肠系膜淋巴结炎。
Pyogranulomatous enteritis and mesenteric lymphadenitis in an adult llama caused by carrying virulence-associated protein A gene.
作者信息
Löhr Christiane V, O'Neill T William, Daw Danielle N, Pitel Mariya O, Schlipf John W
机构信息
Oregon Veterinary Diagnostic Laboratory, Departments of Biomedical Sciences (Löhr, O'Neill).
Clinical Sciences (Daw, Pitel, Schlipf), Carlson College of Veterinary Medicine, Oregon State University, Corvallis, OR.
出版信息
J Vet Diagn Invest. 2019 Sep;31(5):747-751. doi: 10.1177/1040638719862834. Epub 2019 Jul 5.
We report herein infection in an 11-y-old, male llama with a history of diarrhea and endoparasitism. Postmortem examination revealed granulomatous and ulcerative enteritis, pyogranulomatous mesenteric lymphadenitis, fibrinosuppurative peritonitis, and granulomatous hepatitis. Intralesional macrophages were laden with gram-positive cocci. Bacteriology identified , and cultures tested positive for and genes by PCR. This case expands the reported spectrum of lesions associated with infections in llamas from pyogranulomatous bronchopneumonia and peripheral lymphadenitis to pyogranulomatous mesenteric lymphadenitis and enteritis. We also link a that is carrying the virulent-associated protein gene to clinical disease in New World camelids.
我们在此报告一例11岁雄性美洲驼感染病例，该美洲驼有腹泻和体内寄生虫感染史。尸检显示为肉芽肿性和溃疡性肠炎、脓性肉芽肿性肠系膜淋巴结炎、纤维蛋白化脓性腹膜炎和肉芽肿性肝炎。病灶内巨噬细胞充满革兰氏阳性球菌。细菌学鉴定显示，通过聚合酶链反应（PCR）检测，培养物对[具体细菌名称1]和[具体细菌名称2]基因呈阳性。该病例扩大了已报道的与美洲驼[具体细菌名称]感染相关的病变范围，从脓性肉芽肿性支气管肺炎和外周淋巴结炎扩展到脓性肉芽肿性肠系膜淋巴结炎和肠炎。我们还将携带毒力相关蛋白基因[具体基因名称]的[具体细菌名称]与新大陆骆驼科动物的临床疾病联系起来。
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