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在《动物卫生法》(欧盟第2016/429号条例)框架内对动物疾病进行列名和分类的评估:马匹中的抗菌药物耐药性

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): antimicrobial-resistant in horses.

作者信息

Nielsen Søren Saxmose, Bicout Dominique Joseph, Calistri Paolo, Canali Elisabetta, Drewe Julian Ashley, Garin-Bastuji Bruno, Gonzales Rojas José Luis, Gortázar Christian, Herskin Mette, Michel Virginie, Miranda Chueca Miguel Ángel, Padalino Barbara, Pasquali Paolo, Roberts Helen Clare, Spoolder Hans, Ståhl Karl, Velarde Antonio, Viltrop Arvo, Winckler Christoph, Baldinelli Francesca, Broglia Alessandro, Kohnle Lisa, Alvarez Julio

出版信息

EFSA J. 2022 Feb 2;20(2):e07081. doi: 10.2903/j.efsa.2022.7081. eCollection 2022 Feb.

Abstract

() was identified among the most relevant antimicrobial-resistant (AMR) bacteria in the EU for horses in a previous scientific opinion. Thus, it has been assessed according to the criteria of the Animal Health Law (AHL), in particular criteria of Article 7 on disease profile and impacts, Article 5 on its eligibility to be listed, Annex IV for its categorisation according to disease prevention and control rules as in Article 9 and Article 8 for listing animal species related to the bacterium. The assessment has been performed following a methodology previously published. The outcome is the median of the probability ranges provided by the experts, which indicates whether each criterion is fulfilled (lower bound ≥ 66%) or not (upper bound ≤ 33%), or whether there is uncertainty about fulfilment. Reasoning points are reported for criteria with uncertain outcome. According to the assessment here performed, it is uncertain whether AMR can be considered eligible to be listed for Union intervention according to Article 5 of the AHL (10-66% probability). According to the criteria in Annex IV, for the purpose of categorisation related to the level of prevention and control as in Article 9 of the AHL, the AHAW Panel concluded that the bacterium does not meet the criteria in Sections 1 and 2 (Categories A and B; 5-10% and 10-33% probability of meeting the criteria, respectively), and the AHAW Panel is uncertain whether it meets the criteria in Sections 3, 4 and 5 (Categories C, D and E; 10-66% probability of meeting the criteria in all three categories). The animal species to be listed for AMR according to Article 8 criteria are mainly horses and other species belonging to the Perissodactyla and Artiodactyla orders.

摘要

在之前的一项科学意见中,(某细菌)被确定为欧盟马匹中最相关的耐抗菌药物(AMR)细菌之一。因此,已根据《动物卫生法》(AHL)的标准进行了评估,特别是关于疾病概况和影响的第7条标准、关于其列入资格的第5条标准、根据第9条疾病预防和控制规则进行分类的附件IV以及关于列出与该细菌相关动物物种的第8条标准。评估是按照先前公布的方法进行的。结果是专家提供的概率范围的中位数,这表明每个标准是否得到满足(下限≥66%)或未得到满足(上限≤33%),或者是否存在关于满足情况的不确定性。对于结果不确定的标准,报告了推理要点。根据此处进行的评估,不确定是否可以根据AHL第5条将AMR视为有资格列入欧盟干预清单(概率为10 - 66%)。根据附件IV中的标准,为了与AHL第9条中的预防和控制水平相关的分类目的,动物卫生和福利专家组得出结论,该细菌不符合第1和第2节中的标准(A类和B类;满足标准的概率分别为5 - 10%和10 - 33%),并且动物卫生和福利专家组不确定它是否符合第3、4和5节中的标准(C类、D类和E类;在所有三个类别中满足标准的概率为10 - 66%)。根据第8条标准,拟为AMR列出的动物物种主要是马以及其他属于奇蹄目和偶蹄目的物种。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4032/8808660/0b8ad9ccb224/EFS2-20-e07081-g027.jpg

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