Section of Cardiology, Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.
McMaster University, Hamilton, Ontario, Canada.
Transfusion. 2019 Sep;59(9):2865-2869. doi: 10.1111/trf.15442. Epub 2019 Jul 5.
Adverse events during donation negatively impact the likelihood of subsequent donation. Syncope is a possible complication of blood donation in healthy individuals. This systematic review aims to identify risk factors for syncope in healthy blood donors.
Medline, Embase, Cochrane, CINAHL, Web of Science, Transfusion Evidence Library, and PubMed libraries up to November 2016 were searched. Inclusion criteria were observational and interventional trials, case series including more than 10 participants, randomized controlled trials, and clinical trials. Papers required data pertaining to syncopal events separate from presyncope for inclusion. Incomplete text or non-English language versions were excluded. Papers were evaluated using the CHARMS 2014 checklist.
From 3316 papers, 1297 unique citations were identified, and 11 were selected for data extraction. Sex, estimated blood volume, age, donor status, blood pressure, heart rate, weight, previous reaction, caffeine, sleep, and donation site were identified as risk factors for syncope during blood donation.
Possible risk factors for syncope in healthy blood donors have been identified that could allow for improved screening prior to donation and potential reduction in donor attrition due to negative experiences.
捐献过程中的不良反应会降低后续捐献的可能性。晕厥是健康个体献血的一种可能并发症。本系统综述旨在确定健康献血者晕厥的危险因素。
截至 2016 年 11 月，检索了 Medline、Embase、Cochrane、CINAHL、Web of Science、输血证据图书馆和 PubMed 数据库。纳入标准为观察性和干预性试验、包括 10 例以上参与者的病例系列、随机对照试验和临床试验。入选论文需单独报告晕厥事件数据，排除不完整文本或非英文版本的论文。使用 CHARMS 2014 清单评估论文。
从 3316 篇论文中确定了 1297 条独特的引用，选择了 11 篇论文进行数据提取。性别、估计血容量、年龄、献血者身份、血压、心率、体重、既往反应、咖啡因、睡眠和献血部位被确定为献血过程中晕厥的危险因素。
已经确定了健康献血者晕厥的可能危险因素，这可以在献血前进行更好的筛查，并通过减少因负面体验而导致的献血者流失，潜在地降低这种风险。
