Fatigue behavior of stent in tapered arteries: The role of arterial tapering and stent material.

Stenting has achieved great success in treating cardiovascular diseases due to its high efficiency and minimal invasiveness. However, fatigue of stents severely limits its long-term outcome. In this article, finite element method was adopted to study the effects of arterial tapering and stent material on the fatigue performance of stents. A series of tapered vessels with different taper levels and two sets of stents with different materials were modeled. The Goodman diagram was used to evaluate the fatigue resistance of stents. Results showed that the fatigue resistance of stents can be extremely improved by simply changing stent material. In addition, the taper of the arteries had an important influence on the fatigue resistance of the stent. The fatigue life of the stent will be shortened with the increase of the arterial taper. The method that predicted stent fatigue life in tapered vessels can help clinicians select stents that are more suitable for tapered vessels and help stent engineers design stents that are more resistant to fatigue.