School of Mechanical Engineering, Jiangsu University, Zhenjiang, China.
Department of Mechanical Engineering, University of Nebraska-Lincoln, Lincoln, NE, USA.
Artif Organs. 2020 Jul;44(7):727-735. doi: 10.1111/aor.13661. Epub 2020 Mar 1.
The natural tapering of coronary arteries often creates a dilemma for optimal balloon sizing during stenting. The influence of different balloon types, namely, a tapered balloon and a conventional cylindrical balloon, on the mechanical performance of the stent as well as arterial mechanics was investigated via the finite element method. Stent free-expansion and stent deployment in a stenotic tapered artery were investigated numerically. The biomechanical behavior of the two balloon types was compared in terms of stent foreshortening, stent deformation, stent stress distribution, and arterial wall stress distribution. Results indicate that balloon types affect the transient behavior of the stent and the arterial mechanics. Specifically, a tapered balloon could maintain the natural tapering of the coronary artery after stent expansion. In contrast to a cylindrical balloon, tapered balloon also mitigated the foreshortening of the stent (7.69%) as well as the stress concentration in the stent and artery (8.61% and 4.17%, respectively). Hence, tapered balloons should be used in tapered arteries as they may result in low risk of artery injury. This study might provide insights for improved balloon choice and presurgical planning.
冠状动脉的自然锥形常常给支架置入术中的最佳球囊尺寸选择带来难题。通过有限元方法研究了不同球囊类型(即锥形球囊和传统的圆柱形球囊)对支架的机械性能和动脉力学的影响。数值研究了狭窄锥形动脉中的支架自由扩张和支架部署。从支架缩短、支架变形、支架应力分布和动脉壁应力分布等方面比较了两种球囊类型的生物力学行为。结果表明,球囊类型会影响支架的瞬态行为和动脉力学。具体来说,锥形球囊可以在支架扩张后保持冠状动脉的自然锥形。与圆柱形球囊相比,锥形球囊还可以减轻支架缩短(7.69%)以及支架和动脉的应力集中(分别为 8.61%和 4.17%)。因此,在锥形动脉中应使用锥形球囊,因为它们可能导致较低的动脉损伤风险。本研究可能为改进球囊选择和术前规划提供思路。