Unité d'Évaluation des Technologies et des Modes d'Intervention en Santé and Centre de Recherche du Centre hospitalier universitaire de Sherbrooke, Centre Intégré Universitaire de Santé et Services Sociaux de l'Estrie-CHUS, Sherbrooke, QC, Canada.
Department of Economics, University of Sherbrooke, Sherbrooke, QC, Canada.
Value Health. 2019 Jul;22(7):837-842. doi: 10.1016/j.jval.2018.12.012. Epub 2019 May 17.
The Short Form 6 Dimension (SF-6D) is a multi-attribute utility instrument derived from the Short-Form 36 Health Survey Version 2 (SF-36v2) quality of life questionnaire and is used to calculate quality-adjusted life years (QALYs) on a scale 0 to 1. The SF-6Dv2 is a new version of the SF-6D.
The aim of this study was to assess the consistency of respondents' answers to 3 different methods to administer this new version.
SF-6Dv2 utility values were generated from the SF-36v2 using the following: (1) full questionnaire with 36 items (SF-6Dv2); (2) subset questionnaire with 10 items (SF-6Dv2); (3) SF-6Dv2 administered as an independent instrument (rephrased questionnaire with only 6 items [SF-6Dv2]). The order of the 3 instruments was randomly allocated between respondents.
A total of 782 respondents from Quebec, Canada, were interviewed, out of whom 697 fully completed the survey. Very few deviations in respondents' answers were observed between the 3 instruments, with mean weighted kappa of 0.79 (range 0.61-0.91) and mean global consistency index of 70% (range 54-83). Maximal difference in utility values generated was found between SF-6Dv2 and SF-6Dv2 (mean difference 0.016, P < .01), whereas minimal difference was found between SF-6Dv2 and SF-6Dv2 (0.002, P = .38). No ceiling effect was observed.
The SF-6Dv2 was designed to derive utilities from the SF-36v2, and our results indicate that it is still preferable to use the full questionnaire, although the difference with other variants of the questionnaire is very small. To use the SF-6Dv2 as an independent instrument will thus introduce minimal bias in utility values generated.
简短表格 6 维度（SF-6D）是一种源自简短表格 36 健康调查版本 2（SF-36v2）的多维效用工具，用于在 0 到 1 的范围内计算质量调整生命年（QALYs）。SF-6Dv2 是 SF-6D 的新版本。
本研究旨在评估受访者对 3 种不同管理新版本方法的答案的一致性。
使用以下方法从 SF-36v2 生成 SF-6Dv2 效用值：（1）包含 36 个项目的完整问卷（SF-6Dv2）；（2）包含 10 个项目的子问卷（SF-6Dv2）；（3）作为独立工具管理的 SF-6Dv2（重新表述的只有 6 个项目的问卷[SF-6Dv2]）。受访者之间随机分配 3 种仪器的顺序。
从加拿大魁北克省共采访了 782 名受访者，其中 697 名受访者完整完成了调查。在 3 种仪器之间，受访者的答案几乎没有偏差，加权平均 kapp 值为 0.79（范围为 0.61-0.91），平均总体一致性指数为 70%（范围为 54-83）。在效用值生成中发现 SF-6Dv2 和 SF-6Dv2 之间的最大差异（平均差异 0.016，P<.01），而 SF-6Dv2 和 SF-6Dv2 之间的最小差异（0.002，P=.38）。未观察到上限效应。
SF-6Dv2 旨在从 SF-36v2 中推导出效用，我们的结果表明，尽管与问卷的其他变体差异很小，但最好还是使用完整的问卷。因此，使用 SF-6Dv2 作为独立工具将在生成的效用值中引入最小的偏差。
