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体力活动参与与南亚成年人慢性病风险的系统评价和荟萃分析。

Physical activity participation and the risk of chronic diseases among South Asian adults: a systematic review and meta-analysis.

机构信息

School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.

Bureau of Integrated Rural Development, Kwame Nkrumah University of Science & Technology, Kumasi, Ghana.

出版信息

Sci Rep. 2019 Jul 5;9(1):9771. doi: 10.1038/s41598-019-46154-3.

Abstract

South Asia specific reviews on the role of physical activity (PA) domains on chronic disease prevention are lacking. This study aimed to systematically review published literature to identify the association between PA domains and chronic diseases and to provide summary estimates of the strength of association. Nine electronic databases were searched using the predefined inclusion criteria which included population (South Asian adults 40 years or older), exposure (PA or sedentary behaviour) and outcome (type 2 diabetes mellitus, breast cancer, colorectal cancer, coronary heart disease, stroke, vascular disease and musculoskeletal diseases and their markers). A random-effects meta-analysis was carried out for cardiometabolic outcomes whereas narrative synthesis was completed for other outcome variables. Inactive or less active South Asian adults were at 31% higher risk of being hypertensive. Likewise, the risk of cardiometabolic outcomes was 1.34 times higher among inactive adults. Household PA was found to have a protective effect  on breast cancer risk. Total and leisure time PA had a protective effect on osteoporosis among males and females respectively. Contemporary studies with a longitudinal design, representative samples, valid and reliable assessment of different domains are needed to establish the role of PA in chronic disease prevention in the region.

摘要

南亚地区缺乏关于身体活动(PA)领域在慢性病预防中的作用的具体评价。本研究旨在系统地综述已发表的文献,以确定 PA 领域与慢性病之间的关联,并提供关联强度的综合估计。使用预定义的纳入标准,在 9 个电子数据库中进行了搜索,纳入标准包括人群(40 岁或以上的南亚成年人)、暴露(PA 或久坐行为)和结局(2 型糖尿病、乳腺癌、结直肠癌、冠心病、中风、血管疾病和肌肉骨骼疾病及其标志物)。对于心血管代谢结局,采用随机效应荟萃分析;对于其他结局变量,则完成叙述性综合分析。不活跃或较少活跃的南亚成年人患高血压的风险高 31%。同样,不活跃成年人患心血管代谢结局的风险高 1.34 倍。家庭 PA 对乳腺癌风险有保护作用。总 PA 和休闲时间 PA 分别对男性和女性的骨质疏松症有保护作用。需要进行具有纵向设计、代表性样本、不同领域的有效和可靠评估的当代研究,以确定 PA 在该地区慢性病预防中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a301/6611898/db842c452113/41598_2019_46154_Fig1_HTML.jpg

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