Department of Newborn and Developmental Pediatrics, Sunnybrook Health Sciences Centre, Toronto, Canada.
Department of Pediatrics, University of Toronto, Toronto, Canada; Department of Pediatrics, Mt Sinai Hospital, Toronto, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada.
J Pediatr. 2019 Nov;214:222-226.e3. doi: 10.1016/j.jpeds.2019.06.027. Epub 2019 Jul 3.
We conducted a retrospective study of 166 ventilator-dependent neonates born extremely preterm in whom patent ductus arteriosus was surgically ligated and evaluated the association of preoperative characteristics and time-to-successful postoperative extubation. Larger patent ductus arteriosus diameter ([>2.5 mm], adjusted hazard ratio 0.51, 95% CI 0.36-0.72) and left-ventricular dilatation (z score ≥2, adjusted hazard ratio 0.61, 95% CI 0.42-0.87) were associated with earlier extubation.
我们对 166 名患有严重早产儿呼吸窘迫综合征且需要使用呼吸机的新生儿进行了回顾性研究，这些新生儿的动脉导管未闭均通过手术结扎，并评估了术前特征与术后成功拔管时间之间的关系。较大的动脉导管未闭直径（[>2.5mm]，调整后的危险比 0.51，95%可信区间 0.36-0.72）和左心室扩张（z 评分≥2，调整后的危险比 0.61，95%可信区间 0.42-0.87）与更早的拔管时间相关。
