Laboratory of Experimental Surgery and Surgical Research N.S. Christeas, National and Kapodistrian University of Athens, Medical School, Athens, Greece
Hellenic Minimally Invasive and Robotic Surgery (MIRS) Study Group, Athens, Greece.
In Vivo. 2019 Jul-Aug;33(4):1373-1379. doi: 10.21873/invivo.11614.
BACKGROUND/AIM: Both bariatric and thyroid surgeries promote calcium and vitamin D deficiency. The correlation, however, of hypocalcemia after thyroidectomy in patients with previous bariatric surgery has been poorly described. This review aimed to investigate the relationship between history of bariatric operations and post-thyroidectomy hypocalcemia, as well as suggested management options.
MEDLINE and Cochrane databases were searched for relevant publications regarding post-thyroidectomy hypocalcemia in patients with previous bariatric surgery.
A total of 17 publications reporting on 126 patients met the inclusion criteria. These included 13 publications about Roux-en-Y gastric bypass (RYGB), 2 regarding biliopancreatic diversion (BPD), 1 about sleeve gastrectomy (SG) and 1 compared three bariatric procedures: SG, RYGB, laparoscopic adjustable gastric band (LAGB). Post-thyroidectomy hypocalcemia was found to be more prevalent in patients with previous RYGB and BPD, but not in previous LAGB and SG.
Patients with previous bariatric surgery are at high risk of post-thyroidectomy hypocalcemia that sometimes leads to higher length of hospital stay and demands more invasive solutions. There is a need, however, for additional studies and further investigation in order to reach more conclusive results.
背景/目的：减重和甲状腺手术都会导致钙和维生素 D 缺乏。然而，既往接受过减重手术的患者在甲状腺切除术后发生低钙血症的相关性尚未得到充分描述。本综述旨在研究既往减重手术史与甲状腺切除术后低钙血症之间的关系，并提出了一些建议的处理方法。
在 MEDLINE 和 Cochrane 数据库中搜索了有关既往接受过减重手术的患者甲状腺切除术后低钙血症的相关文献。
共有 17 项发表的研究报告了 126 名符合纳入标准的患者。这些研究包括 13 项关于 Roux-en-Y 胃旁路术（RYGB）的研究，2 项关于胆胰分流术（BPD）的研究，1 项关于袖状胃切除术（SG）的研究，1 项比较了三种减重手术：SG、RYGB、腹腔镜可调胃束带术（LAGB）。既往接受过 RYGB 和 BPD 的患者发生甲状腺切除术后低钙血症的风险更高，但既往接受过 LAGB 和 SG 的患者则不然。
既往接受过减重手术的患者发生甲状腺切除术后低钙血症的风险较高，这有时会导致更长的住院时间，并需要更具侵入性的治疗方法。然而，为了得出更具结论性的结果，仍需要进行更多的研究和进一步的调查。
