From the Department of Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, Md (J.M.); Department of Obstetrics and Gynecology, George Washington University School of Medicine and Health Sciences, Washington, DC (K.I.M.); University of Illinois College of Medicine, Peoria, Ill (S.L.P.); Department of Pathology, the Joint Pathology Center, Washington, DC (B.A.C., R.M.); American Institute for Radiologic Pathology, 1100 Wayne Ave, Suite 1020, Silver Spring, MD 20910 (J.M., D.J.W.); and Community Radiology Division, Department of Radiology, Johns Hopkins Hospital and Health System, Washington, DC (D.J.W.).
Radiographics. 2019 Jul-Aug;39(4):982-997. doi: 10.1148/rg.2019180221.
Mucinous neoplasms of the ovary account for 10%-15% of ovarian neoplasms. They may be benign, borderline, or malignant. The large majority are benign or borderline, accounting for 80% and 16%-17%, respectively. Mucinous neoplasms of the ovary most commonly affect women in their 20s to 40s. The clinical manifestation is nonspecific, but most mucinous ovarian neoplasms manifest as large unilateral pelvic masses. At gross pathologic analysis, mucinous ovarian neoplasms appear as large multiloculated cystic masses. The contents of the cyst loculi vary on the basis of differences in internal mucin content. At histologic analysis, mucinous ovarian neoplasms are composed of multiple cysts lined by mucinous epithelium, often resembling gastrointestinal-type epithelium. Imaging evaluation most commonly includes US and/or MRI. The imaging findings parallel the gross pathologic features and include a large, unilateral, multiloculated cystic mass. The cyst loculi vary in echogenicity, attenuation, and signal intensity depending on the mucin content. Mucinous neoplasms of the ovary are staged surgically using the FIGO (International Federation of Gynecology and Obstetrics) staging system. Primary treatment is surgical, with adjuvant chemotherapy considered in the uncommon case of mucinous carcinoma with extraovarian disease. Since most mucinous ovarian neoplasms are benign or borderline, the overall prognosis is excellent.
卵巢黏液性肿瘤占卵巢肿瘤的 10%-15%。它们可以是良性、交界性或恶性的。绝大多数是良性或交界性的,分别占 80%和 16%-17%。卵巢黏液性肿瘤最常影响 20 多岁到 40 多岁的女性。临床表现是非特异性的,但大多数黏液性卵巢肿瘤表现为单侧大的盆腔肿块。大体病理分析显示,卵巢黏液性肿瘤表现为大的多房囊性肿块。囊腔内容物因内部黏液含量的不同而有所不同。组织学分析显示,卵巢黏液性肿瘤由多个黏液上皮衬里的囊组成,常类似于胃肠道型上皮。影像学评估最常见的包括 US 和/或 MRI。影像学表现与大体病理特征平行,包括单侧大的多房囊性肿块。囊腔的回声、衰减和信号强度因黏液含量而异。卵巢黏液性肿瘤采用 FIGO(国际妇产科联合会)分期系统进行手术分期。主要治疗方法是手术,在罕见的伴有卵巢外疾病的黏液性癌的情况下考虑辅助化疗。由于大多数卵巢黏液性肿瘤是良性或交界性的,因此总体预后良好。