Atri Mostafa, Alabousi Abdullah, Reinhold Caroline, Akin Esma A, Benson Carol B, Bhosale Priyadarshani R, Kang Stella K, Lakhman Yulia, Nicola Refky, Pandharipande Pari V, Patel Maitray D, Salazar Gloria M, Shipp Thomas D, Simpson Lynn, Sussman Betsy L, Uyeda Jennifer W, Wall Darci J, Whitcomb Bradford P, Zelop Carolyn M, Glanc Phyllis
Toronto General Hospital, Toronto, Ontario, Canada.
Research Author, McMaster University, Hamilton, Ontario, Canada.
J Am Coll Radiol. 2019 May;16(5S):S77-S93. doi: 10.1016/j.jacr.2019.02.011.
There are approximately 9.1 pelvic surgeries performed for every histologically confirmed adnexal malignancy in the United States, compared to 2.3 surgeries per malignancy (in oncology centers) and 5.9 surgeries per malignancy (in other centers) in Europe. An important prognostic factor in the long-term survival in patients with ovarian malignancy is the initial management by a gynecological oncologist. With high accuracy of imaging for adnexal mass characterization and consequent appropriate triage to subspecialty referral, the better use of gynecologic oncology can improve treatment outcomes. Ultrasound, including transabdominal, transvaginal, and duplex ultrasound, combined with MRI with contrast can diagnose adnexal masses as benign with specific features (ie, functional masses, dermoid, endometrioma, fibroma, pedunculated fibroid, hydrosalpinx, peritoneal inclusion cyst, Tarlov cyst), malignant, or indeterminate. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
在美国,每例经组织学确诊的附件恶性肿瘤大约会进行9.1次盆腔手术,相比之下,在欧洲,每例恶性肿瘤(在肿瘤中心)进行2.3次手术,(在其他中心)每例恶性肿瘤进行5.9次手术。卵巢恶性肿瘤患者长期生存的一个重要预后因素是由妇科肿瘤学家进行初始治疗。随着附件包块特征性成像的高准确性以及随之而来的向专科转诊的适当分流,更好地利用妇科肿瘤学可以改善治疗效果。超声,包括经腹超声、经阴道超声和双功超声,结合增强MRI,可以将具有特定特征的附件包块诊断为良性(即功能性包块、皮样囊肿、子宫内膜异位症、纤维瘤、有蒂肌瘤、输卵管积水、腹膜包涵囊肿、塔尔洛夫囊肿)、恶性或不确定。美国放射学会适宜性标准是针对特定临床情况的循证指南,由多学科专家小组每年进行审查。指南的制定和修订包括对同行评审期刊上的当前医学文献进行广泛分析,以及应用成熟的方法(兰德/加州大学洛杉矶分校适宜性方法和推荐分级评估、制定与评价或GRADE)来评估特定临床场景下成像和治疗程序的适宜性。在缺乏证据或证据不明确的情况下,专家意见可能会补充现有证据以推荐成像或治疗。