Omura Miyuki, Sarkar Rupak Kumar, Sankar Ajesh
Barnsley Hospital NHS Foundation Trust, Obstetrics and Gynaecology Department, Barnsley Hospital, South Yorkshire, UK.
J Reprod Infertil. 2025 Jan-Mar;26(1):64-68. doi: 10.18502/jri.v26i1.18783.
The recurrence of benign ovarian mucinous cystadenomas is rare, and the presence of these cysts bilaterally is even more uncommon. Overall, 11 cases in our literature review were identified. Of these recurrences, only two cases were bilateral. The management of ovarian cysts in young patients is challenging, especially if they recur. Laparoscopic surgery is the most common intervention for ovarian cysts and a conservative approach using ovarian cystectomy is preferred in women in the reproductive age group.
A 16-year-old nulliparous female was admitted with persistent lower abdominal pain and bloating. A pelvic magnetic resonance imaging showed large bilateral cystic and multiloculated adnexal masses arising from her ovaries. Her tumor markers were normal. The patient underwent three seperate ovarian cystectomies over a seven-year period from the age of sixteen due to recurrent large bilateral benign ovarian mucinous cystadenomas. Repeated histological examinations were the same after each case. Given her age and the history of multiple ovarian surgeries, she was referred to the fertility clinic to explore options for oocyte cryopreservation.
This unusual case of bilateral recurrent benign ovarian mucinous cystadenomas underscores the importance of early laparoscopy and cystectomy as a recommended approach. Postoperative transvaginal ultrasound scans during follow-up may assist in the early detection of recurrence cases. Clinicians should strongly consider referring young patients with a history of repeated adnexal surgeries to infertility treatment centers for fertility preservation.
卵巢良性黏液性囊腺瘤复发罕见,双侧出现此类囊肿更为少见。在我们的文献综述中,共识别出11例。在这些复发病例中,仅2例为双侧。年轻患者卵巢囊肿的处理具有挑战性,尤其是囊肿复发时。腹腔镜手术是卵巢囊肿最常见的干预方式,对于育龄期女性,采用卵巢囊肿切除术的保守方法更为可取。
一名16岁未生育女性因持续下腹痛和腹胀入院。盆腔磁共振成像显示双侧卵巢有巨大的囊性和多房性附件肿块。她的肿瘤标志物正常。该患者从16岁起的7年时间里,因双侧复发性巨大良性卵巢黏液性囊腺瘤接受了三次单独的卵巢囊肿切除术。每次术后重复的组织学检查结果均相同。鉴于她的年龄和多次卵巢手术史,她被转诊至生育门诊,以探讨卵母细胞冷冻保存的方案。
双侧复发性良性卵巢黏液性囊腺瘤的这一罕见病例强调了早期腹腔镜检查和囊肿切除术作为推荐方法的重要性。随访期间的术后经阴道超声扫描可能有助于早期发现复发病例。临床医生应强烈考虑将有多次附件手术史的年轻患者转诊至不育治疗中心进行生育力保存。