Bax A, Summers M F, Egan W, Guirgis N, Schneerson R, Robbins J B, Orskov F, Orskov I, Vann W F
Laboratory of Chemical Physics, National Institute of Diabetes, Digestive, and Kidney Diseases, Bethesda, Maryland 20892.
Carbohydr Res. 1988 Feb 15;173(1):53-64. doi: 10.1016/s0008-6215(00)90802-4.
The structures of the Escherichia coli K93 and K53 capsular polysaccharides have been investigated by chemical and spectroscopic methods. The repeating unit of both polymers was found to be----3)-beta-D-Galf-(1----f)-beta-D-GlcAp-(1. The O-5 and O-6 atoms of D-galactose are acetylated in the repeating unit of the K93 polymer, but only O-2 is acetylated in the K53 polymer. The K93 polysaccharide is cross-reactive with the Neisseria meningitidis Group A capsular polysaccharide (of known structure). The K53 polysaccharide, although structurally similar to that from K93 organisms, does not cross-react with the Group A polymer.
已通过化学和光谱方法研究了大肠杆菌K93和K53荚膜多糖的结构。发现这两种聚合物的重复单元均为----3)-β-D-半乳糖基-(1----f)-β-D-葡萄糖醛酸-(1。在K93聚合物的重复单元中，D-半乳糖的O-5和O-6原子被乙酰化，但在K53聚合物中只有O-2被乙酰化。K93多糖与已知结构的A群脑膜炎奈瑟菌荚膜多糖有交叉反应。K53多糖虽然在结构上与K93菌株的多糖相似，但与A群聚合物无交叉反应。
