Tsui F P, Boykins R A, Egan W
Carbohydr Res. 1982 Apr 16;102:263-71. doi: 10.1016/s0008-6215(00)88068-4.
The structure of the Escherichia coli K7 capsular polysaccharide has been investigated by a combination of chemical and spectroscopic methods. The Structure of the repeating unit of the polymer was found to be goes to 3)-beta-D-ManNAcA-(1 leads to 4)-beta-D-Glc-(1 goes to ; the O-6 atom of the D-glucosyl residue in the repeating unit is acetylated. The K7 polysaccharide is cross-reactive with the Streptococcus pneumoniae type 3 polysaccharide, the structure of which had previously been determined; our n.m.r. studies of the S. pneumoniae type 3 polysaccharide are in accord with this structure. The E. coli K7 and K56 capsular antigens have been shown by serology and 13C-n.m.r. spectroscopy to be identical.
通过化学和光谱方法相结合的方式对大肠杆菌K7荚膜多糖的结构进行了研究。发现该聚合物重复单元的结构为→3)-β-D-甘露糖醛酸-(1→4)-β-D-葡萄糖-(1→；重复单元中D-葡萄糖基残基的O-6原子被乙酰化。K7多糖与先前已确定结构的肺炎链球菌3型多糖有交叉反应；我们对肺炎链球菌3型多糖的核磁共振研究与该结构相符。血清学和13C核磁共振光谱显示大肠杆菌K7和K56荚膜抗原是相同的。
