Department of Environmental Health, School of Public Health, Tehran University of Medical Science, Tehran, Iran.
Department of Environmental Health, School of Public Health, Tehran University of Medical Science, Tehran, Iran; Center for Air Pollution Research (CAPR), Institute for Environmental Research (IER), Tehran University of Medical Sciences, Tehran, Iran.
Food Chem. 2019 Nov 30;299:125126. doi: 10.1016/j.foodchem.2019.125126. Epub 2019 Jul 3.
The health risk assessment of exposure to toxic metals through the consumption food crops is very important. The present study was aimed to investigate the bioaccessibility of toxic metals (including arsenic, lead and cadmium) in rice through an in vitro gastrointestinal digestion model, and assess health risks associated with these metals in raw, cooked and digested rice. Total and bioaccessible concentration of metals were measured by introducing the prepared samples into the inductively coupled plasma-optical emission spectroscopy. Based on the results, the bioaccessible toxic metals in gastric phase were significantly higher than that in both oral and small intestinal phases. The estimated concentrations of these metals in the raw and cooked rice are very far from the actual exposure state. Therefore, to assess the extent of health risks associated with the subjected toxic metals through the rice consumption, the actual exposure value of the metals (bioaccessible value) should be considered.
通过食用农作物接触有毒金属的健康风险评估非常重要。本研究旨在通过体外胃肠道消化模型研究大米中有毒金属（包括砷、铅和镉）的生物可给性，并评估生米、熟米和消化米中这些金属带来的健康风险。通过将制备好的样品引入电感耦合等离子体-光学发射光谱法来测量金属的总量和生物可给浓度。结果表明，在胃相中，生物可给有毒金属的浓度明显高于口腔相和小肠相。在生米和熟米中这些金属的估计浓度与实际暴露状态相差甚远。因此，为了通过食用大米来评估与摄入的有毒金属相关的健康风险程度，应考虑这些金属的实际暴露值（生物可给值）。
