Kaiser Permanente Washington Health Research Institute, Seattle, Washington
Kaiser Permanente Washington Health Research Institute, Seattle, Washington.
Ann Fam Med. 2019 Jul;17(4):319-325. doi: 10.1370/afm.2390.
Six key elements of opioid medication management redesign in primary care have been previously identified. Here, we examine the effect of implementing these Six Building Blocks on opioid-prescribing practices.
Six rural-serving organizations with 20 clinic locations received support for 15 months during the period October 2015 to May 2017 to implement the Six Building Blocks. Patients undergoing long-term opioid therapy (LtOT) at these study sites were compared with patients undergoing LtOT enrolled in a regional health plan who did not receive care at the study sites but who resided in the same primary care service areas (control group). Outcomes were monthly trend in the proportion of patients undergoing LtOT prescribed a ≥100 morphine equivalent dose (MED) of opioids daily and the total number of patients receiving an opioid prescription. An interrupted time series using difference-indifference analysis was used for tests of significance.
The proportion of patients prescribed a ≥100 MED of opioids daily decreased 2.2% (11.8% to 9.6%) among patients at the intervention clinics and 1.3% (14.0% to 12.7%) among patients in the control group. The rate of decrease was significantly greater among study patients than among patients in the control group ( = .018). The rate of decrease in the number of patients on LtOT at intervention clinics increased during the intervention period compared with the preintervention period ( <.001).
Efforts to redesign opioid medication management in primary care resulted in a significant decrease in opioid prescribing. Future research is needed to determine if these results are generalizable to other settings and to assess implications for patient-reported outcomes.
先前已经确定了初级保健中阿片类药物管理重新设计的六个关键要素。在这里,我们研究了实施这六个构建块对阿片类药物处方实践的影响。
在 2015 年 10 月至 2017 年 5 月期间,六个为农村服务的组织在 20 个诊所获得了 15 个月的支持,以实施这六个构建块。与未在研究地点接受护理但居住在同一初级保健服务区域(对照组)的接受长期阿片类药物治疗(LtOT)的患者相比,在这些研究地点接受 LtOT 的患者接受了比较。结果是每月接受 LtOT 治疗的患者中,处方每日至少 100 吗啡当量剂量(MED)的患者比例和接受阿片类药物处方的患者总数的趋势。使用差异差异分析的中断时间序列用于显著性检验。
干预诊所患者每日处方 ≥100 MED 阿片类药物的患者比例下降 2.2%(11.8%至 9.6%),对照组患者下降 1.3%(14.0%至 12.7%)。研究患者的下降速度明显快于对照组患者(<0.018)。干预期间,干预诊所接受 LtOT 治疗的患者人数减少率高于干预前(<0.001)。
在初级保健中重新设计阿片类药物管理的努力导致阿片类药物处方的显著减少。需要进一步研究以确定这些结果是否可推广到其他环境,并评估对患者报告结果的影响。