Congenital and juvenile glaucoma are associated with goniodysgenesis and currently thought to be the result of neural crest cell abnormal terminal induction or migration. Infantile glaucoma may be primary, or may be associated with syndromes such as Sturge-Weber, Rieger's and others. Differentiation from other childhood causes of cloudy cornea such as endothelial dystrophies is essential. Evaluations under anesthesia are often needed and present their own problems in diagnosis.