Stroupe Kevin T, Smith Bridget, Weaver Frances M, Gonzalez Beverly, Huo Zhiping, Cao Lishan, Ippolito Dolores, Follett Kenneth A
Center of Innovation for Complex Chronic Healthcare Hines VA Hospital Hines IL.
Loyola University Stritch School of Medicine Maywood IL.
Mov Disord Clin Pract. 2019 Apr 22;6(5):369-378. doi: 10.1002/mdc3.12765. eCollection 2019 Jun.
To compare the complications, healthcare utilization and costs following DBS or medical management for patients with Parkinson's disease (PD).
We examined healthcare utilization and costs for up to 5 years between veterans with DBS and those with medical management for PD. Veterans who received DBS between 2007 and 2013 were matched with veterans who received medical management using propensity score approaches. Healthcare utilization and costs were obtained from national VA and Medicare data sources and compared using procedures to adjust for potential differences in length of follow-up.
We identified 611 veterans who had received DBS and a matched group of 611 veterans who did not undergo DBS. Among DBS patients, 59% had the electrodes and generator implanted during separate admissions. After 5 years of follow-up, average total healthcare costs, including DBS procedures and complications, were $77,131 (95% confidence interval: $66,095-$88,168; < 0.001) higher per person for patients who received DBS ($162,489) than patients who received medical management ($85,358). In contrast, excluding the costs of the DBS procedures and complications, average total costs were not significantly different between patients who received DBS and patients who received medical management after 5 years of follow-up.
Healthcare costs over 5 years were higher for veterans who received DBS. These higher healthcare costs may reflect the costs of DBS procedures and any follow-up required plus greater surveillance by healthcare professionals following DBS as well as unobserved differences in the patients who received medical management or DBS.
比较帕金森病(PD)患者接受脑深部电刺激术(DBS)或药物治疗后的并发症、医疗资源利用情况及费用。
我们研究了接受DBS治疗的退伍军人和接受PD药物治疗的退伍军人长达5年的医疗资源利用情况及费用。使用倾向评分法将2007年至2013年间接受DBS治疗的退伍军人与接受药物治疗的退伍军人进行匹配。医疗资源利用情况及费用数据来自国家退伍军人事务部(VA)和医疗保险数据来源,并采用调整随访时间潜在差异的程序进行比较。
我们确定了611名接受DBS治疗的退伍军人以及611名未接受DBS治疗的匹配退伍军人组。在接受DBS治疗的患者中,59%在不同的住院期间植入了电极和发生器。经过5年的随访,接受DBS治疗的患者(162,489美元)每人的平均总医疗费用,包括DBS手术及并发症,比接受药物治疗的患者(85,358美元)高出77,131美元(95%置信区间:66,095美元 - 88,168美元;<0.001)。相比之下,排除DBS手术及并发症的费用后,经过5年随访,接受DBS治疗的患者与接受药物治疗的患者平均总费用无显著差异。
接受DBS治疗的退伍军人5年的医疗费用更高。这些较高的医疗费用可能反映了DBS手术的费用、任何所需的后续治疗费用,以及DBS治疗后医疗专业人员加强的监测,还有接受药物治疗或DBS治疗的患者中未观察到的差异。