用同基因三硝基苯基偶联膜诱导细胞毒性T淋巴细胞。
The induction of cytolytic T lymphocytes with syngeneic trinitrophenyl-coupled membranes.
作者信息
Sherman L, Mescher M F, Burakoff S J
出版信息
J Immunol. 1979 Jul;123(1):501-2.
PMID:312884
Abstract
Evidence is presented that trinitrophenyl-coupled tumor membranes are able to induce cytolytic T lymphocytes (CTL) when co-cultured with syngeneic spleen cells. These haptenated membranes stimulate spleen cells from naive and immune mice. The specificity of these CTL is determined by the H-2 antigens of the membranes used for stimulation.
摘要
有证据表明，三硝基苯基偶联的肿瘤细胞膜与同基因脾细胞共培养时能够诱导细胞毒性T淋巴细胞（CTL）。这些半抗原化的膜刺激来自未免疫和免疫小鼠的脾细胞。这些CTL的特异性由用于刺激的膜的H-2抗原决定。
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